Hyperpolarized MRSI in Ischemic Heart Disease: A Metabolic Investigation of the Heart Muscle
Hyperpolarized MRSI in Ischemic Heart Disease: Metabolic Profiling of the Myocardium
This study is testing a new imaging technique to see how heart muscle metabolism is affected in people with ischemic heart disease.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 15 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Aarhus University Hospital Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Aarhus, Central Jutland) |
| Trial ID | NCT06054516 on ClinicalTrials.gov |
What this trial studies
Processing failed - manual review needed
Who should consider this trial
Good fit: Unknown
Not a fit: Unknown
Why it matters
Potential benefit: Unknown
How similar studies have performed: Unknown
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Chronic heart failure * \>18 years of age * Left ventricular Ejection Fraction (LVEF) of 10 - 60 % * Adequate hematologic and organ function. * Women who are not postmenopausal or surgically sterile must have a negative serum or urine pregnancy test performed at time of inclusion in the study. * Safe and highly effective contraception must be used throughout the study meaning either hormonal anti-conception or an anti-fertility intrauterine device. If the partner is non fertile or the patient has no sexual activities, this is also accepted. * Non-insulin dependent Diabetes mellitus is allowed * Danish speaking * Able and willing to comply after informed consent * Ischemic heart disease and referral to viability testing at the Department of Clinical Physiology and Nuclear Medicine at Aarhus University Hospital. Exclusion Criteria: * Not able or willing to receive heart failure therapy * Patients not willing to participate * Uncontrolled serious medical condition, such as uncontrolled heart disease, uncontrolled diabetes, intestinal obstruction, uncontrolled hypertension, or recent cerebral ischemia * Estimated Glomerular Filtration Rate (eGFR) \<30 mL/min * Insulin dependent Diabetes Mellitus * Intolerance to Pyruvate
Where this trial is running
Aarhus, Central Jutland
- Aarhus University Hospital — Aarhus, Central Jutland, Denmark (Recruiting)
Study contacts
- Study coordinator: Niels A. Jespersen, MD
- Email: nijesp@rm.dk
- Phone: +4522950990
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions
Ischemic Heart Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team.
Information on this page is for educational purposes and is not medical advice.
Always consult qualified healthcare professionals about clinical trial participation.