Hydrogen water to reduce fatigue and improve function in ME/CFS

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot interventional study enrolls adults with ME/CFS and gives hydrogen water made from an over-the-counter magnesium-based supplement using a 10-day graduated dosing schedule followed by a standard daily dose for 16 weeks. Participants will be monitored for changes in fatigue-related symptoms and physical functioning, and heart rate variability (HRV) will be measured as a candidate biomarker. Investigators plan to identify two outcome subgroups—improvers and non-improvers—and test whether higher baseline HRV predicts clinical improvement. The single-site study at Stony Brook University is intended to generate preliminary data to guide larger trials.

Why it matters

Who can join: the full rules

Inclusion Criteria: Meets Institute of Medicine criteria for myalgic encephalomyelitis/chronic fatigue syndrome -

Exclusion Criteria: Medical illness that explains presenting fatigue; Any psychosis.

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Where it's running

• Stony Brook University
  Stony Brook, New York, United States Recruiting

Study contacts

• Principal investigator: Fred Friedberg, PhD — Stony Brook University
• Study coordinator: Fred Friedberg, PhD
• Email: fred.friedberg@stonybrookmedicine.edu
• Phone: 15167024213

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.