Hyaluronic Acid Injections for Skin Health in Healthy Adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study uses intracutaneous injections of a hyaluronic acid–based formulation to explore changes in biological markers related to skin health and fibroblast activity. The goal is to determine if these biological changes occur and whether they correspond with any observable improvements in skin quality. Participants are healthy volunteers and will undergo a series of procedures and visits under supervision at Geneva University Hospitals. The study focuses on objective biological endpoints rather than subjective aesthetic outcomes.

Why it matters

Who can join: the full rules

Inclusion criteria:

* Informed Consent signed by the subject
* Healthy adult volunteers aged 18 to 50 years at the time of inclusion
* Ability and willingness to comply with all study procedures and visits as required by the protocol.

Exclusion criteria:

* Pregnant or breastfeeding women, or women unwilling to use an effective method of contraception, as the use of the investigational medical device is contraindicated according to the Instructions for Use (IFU)
* Known hypersensitivity to any of the product ingredients, as well as fructose intolerance.
* Any skin disease or systemic disease that, in the opinion of the investigator, may affect the treatment area or interfere with study assessments.
* Presence of any skin alteration at the test sites, including but not limited to scars, tattoos, or other visible skin lesions.
* History of hypertrophic scars or keloid formation or a similar abnormal wound healing.
* Presence of terminal hairs at the designated test sites.
* Current use of any medication or treatment that, in the judgment of the investigator, may interfere with the interpretation of study results or pose a safety concern.
* Body Mass Index (BMI) \> 36 kg/m².
* Any medical, psychological, psychiatric, or cognitive condition, including drug or alcohol abuse, language barriers, or other circumstances that, in the opinion of the investigator, may impair the subject's ability to understand the study information, comply with the investigation procedures, or complete the investigation.
* Participation in another clinical investigation involving an investigational medicinal product or medical device within the 30 days prior to enrolment.
* Previous enrolment in the current investigation.
* Enrolment of the principal investigator, sub-investigators, their family members, employees, or other dependent persons.

Where it's running

• Geneva University Hospitals (HUG)
  Geneva, Switzerland Recruiting

Study contacts

• Study coordinator: Hans Joachim Laubach, MD
• Email: hlau@hug.ch
• Phone: +41 22 372 9450

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.