Clinical trial Recruiting at 2 sites Observational Ages 18 and up Women only

HPV vaccination after treatment for cervical dysplasia

Official title: The Role of Adjuvant VaccInation After Conization for the Treatment for Cervical Dysplasia

Run by Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · NCT06611020 · Data updated 2026-11-12

This study tests whether getting the HPV vaccine after treatment for cervical dysplasia can help prevent the return of HPV-related issues in women.

Quick facts

Study typeObservational
Ages18 Years and up
SexWomen only
Enrollment600 (estimated)
SponsorFondazione IRCCS Istituto Nazionale dei Tumori, Milano
Academic / other
Locations2 sites (Milan, Lombardy and 1 other locations)
StatusRecruiting
StartedJanuary 1, 2020
Main results expectedJanuary 31, 2025
Study endsJanuary 31, 2027
Registry record updatedSeptember 26, 2024
Trial IDNCT06611020 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are women who have been treated for HPV-related cervical lesions but have not previously received HPV vaccination.

Probably not a fit

Patients who have already been vaccinated against HPV will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the potential protective role of HPV vaccination in women who have undergone treatment for HPV-related cervical lesions. Participants will be counseled about the benefits of vaccination and monitored for the risk of HPV recurrence. The study compares outcomes between those who choose to receive the vaccine and those who do not. It aims to gather data on the effectiveness of vaccination in preventing recurrence after excisional treatment.

Why it matters

Potential benefit: If successful, this could significantly reduce the risk of HPV recurrence in women treated for cervical dysplasia.

How similar studies have gone: While there is limited data on this specific approach, previous studies have suggested that HPV vaccination can reduce recurrence rates in similar contexts.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Treatment of HPV-related disease

Exclusion Criteria:

* Previous HPV vaccination

Where it's running

  • Fondazione IRCCS Istituto Nazionale dei Tumori
    Milan, Lombardy, Italy
    Recruiting
  • Fondazione IRCCS Istituto Nazionale dei Tumori
    Milan, Lombardy, Italy
    Recruiting

Study contacts

  • Principal investigator: Grazia Casadei, MD — Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
  • Study coordinator: Giorgio Bogani, ph.d.
  • Email: giorgiobogani@yahoo.it
  • Phone: 651-296-9676

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.