HPV vaccination after treatment for cervical dysplasia
Official title: The Role of Adjuvant VaccInation After Conization for the Treatment for Cervical Dysplasia
Run by Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · NCT06611020 · Data updated 2026-11-12
This study tests whether getting the HPV vaccine after treatment for cervical dysplasia can help prevent the return of HPV-related issues in women.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 600 (estimated) |
| Sponsor | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano Academic / other |
| Locations | 2 sites (Milan, Lombardy and 1 other locations) |
| Status | Recruiting |
| Started | January 1, 2020 |
| Main results expected | January 31, 2025 |
| Study ends | January 31, 2027 |
| Registry record updated | September 26, 2024 |
| Trial ID | NCT06611020 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women who have been treated for HPV-related cervical lesions but have not previously received HPV vaccination.
✕Probably not a fit
Patients who have already been vaccinated against HPV will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the potential protective role of HPV vaccination in women who have undergone treatment for HPV-related cervical lesions. Participants will be counseled about the benefits of vaccination and monitored for the risk of HPV recurrence. The study compares outcomes between those who choose to receive the vaccine and those who do not. It aims to gather data on the effectiveness of vaccination in preventing recurrence after excisional treatment.
Why it matters
Potential benefit: If successful, this could significantly reduce the risk of HPV recurrence in women treated for cervical dysplasia.
How similar studies have gone: While there is limited data on this specific approach, previous studies have suggested that HPV vaccination can reduce recurrence rates in similar contexts.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Treatment of HPV-related disease Exclusion Criteria: * Previous HPV vaccination
Where it's running
-
Fondazione IRCCS Istituto Nazionale dei Tumori
Milan, Lombardy, Italy Recruiting -
Fondazione IRCCS Istituto Nazionale dei Tumori
Milan, Lombardy, Italy Recruiting
Study contacts
- Principal investigator: Grazia Casadei, MD — Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
- Study coordinator: Giorgio Bogani, ph.d.
- Email: giorgiobogani@yahoo.it
- Phone: 651-296-9676
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.