Clinical trial Recruiting at 1 site Observational

HPV types and disease burden of anal cancer in China

Official title: Understanding the Human Papillomavirus Genotype Attribution and Disease Burden of Anal Cancer in China: A Multicenter Hospital-based Study

Run by Fudan University · NCT06670495 · Data updated 2026-11-12

This project will test which HPV types are found in people with anal cancer in China and describe who is affected.

More Anal Cancer trials

Quick facts

Study typeObservational
SexAll
Enrollment300 (estimated)
SponsorFudan University
Academic / other
Drugs / interventionschemotherapy, radiation
Locations1 site (Shanghai)
StatusRecruiting
StartedJune 1, 2025
Main results expectedDecember 31, 2027
Study endsDecember 31, 2028
Registry record updatedFebruary 12, 2026
Trial IDNCT06670495 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults diagnosed with anal cancer in China who have not had radiation or chemotherapy before specimen collection and who consent to provide tumor specimens are ideal candidates.

Probably not a fit

People with HIV, those with post‑transplant immunosuppression, patients who already received chemo/radiation before specimen collection, or cases without available specimens are unlikely to benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will collect tumor specimens and clinical and demographic data from patients diagnosed with anal cancer at Fudan University Shanghai Cancer Center. Tumor samples will be tested for presence and genotype of human papillomavirus (HPV) to determine the distribution of HPV types in anal cancer. The study will also describe epidemiological characteristics, temporal trends, and the overall disease burden of anal cancer in China. Patients with HIV infection, post‑transplant immunosuppression, or who received radiation or chemotherapy before specimen collection are excluded.

Why it matters

Potential benefit: If successful, the findings could guide prevention and screening strategies and inform HPV vaccination and public health policy for anal cancer in China.

How similar studies have gone: International studies have established a strong link between HPV and anal cancer and characterized genotypes elsewhere, but large-scale genotype and burden data specifically from China are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* (1) Patients diagnosed with anal cancers, (2) Patients without radiation or chemotherapy prior to specimen collection;

Exclusion Criteria:

* (1) Patients with HIV infection, (2) Patients with immunosuppression after solid organ transplantation, (3) Those who do not agree to specimen collection and testing, (4) For retrospective study cases, those who without specimen.

Where it's running

  • Fudan University Shanghai Cancer Center
    Shanghai, China
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.