HPV DNA self-sampling in general practitioners' offices
Benefit of Self-sampling for HPV DNA in a General Practitioner's Office to Improve Participation in Cervical Screening - The ASTRA Study.
Patient Organization Veronica · NCT06253169
This study is testing if allowing women to do HPV self-sampling at their doctor's office can help more of them participate in cervical cancer screening.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 30 Years and up |
| Sex | Female |
| Sponsor | Patient Organization Veronica (other gov) |
| Locations | 2 sites (Prague and 1 other locations) |
| Trial ID | NCT06253169 on ClinicalTrials.gov |
What this trial studies
This project aims to evaluate the effectiveness of HPV DNA self-sampling conducted in general practitioners' offices to enhance participation in cervical cancer screening among women in the Czech Republic. With a current participation rate of only 56%, the study seeks to provide an alternative method for women who may be reluctant to visit gynecologists for screening. By allowing self-testing in a familiar setting, the project hopes to increase the number of women who engage in preventive health measures. The study will assess the feasibility and acceptance of this approach among eligible participants.
Who should consider this trial
Good fit: Ideal candidates for this study are women aged 30 and older who have never had an HPV test or have not been tested in the last three years.
Not a fit: Patients who have had a negative HPV test within the last three years or those who regularly participate in cervical screening may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly increase cervical cancer screening rates and improve early detection of HPV-related conditions.
How similar studies have performed: Other studies have shown promise in using self-sampling methods for HPV testing, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Signed informed consent for statistical data processing and consent to the processing of personal data * Age 30+ * HPV test never performed or performed more than 3 years ago or patient does not know Exclusion Criteria: * Refusal to participate * Pregnancy and puerperium * Menses * History of hysterectomy * HPV test performed \<3 years ago with negative result * Regular participation in screening and concurrent age 35, 45 or 55 years (test will be performed in the same year of screening).
Where this trial is running
Prague and 1 other locations
- CGOP, s.r.o. — Prague, Czechia (RECRUITING)
- Department of Gynecology, Obstetrics and Neonatology, General University Hospital, First Faculty of Medicine, Charles University — Prague, Czechia (RECRUITING)
Study contacts
- Study coordinator: Jiří Sláma, MD, PhD
- Email: jiri.slama@vfn.cz
- Phone: +420224967451
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cervical Cancer, HPV Infection, Precancerous Lesion, Prevention, Cervical cancer, HPV test, Self-sampling