How SpO₂ Changes During Reoxygenation After Breath-Holds

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Healthy volunteers will perform voluntary apnea, during which researchers will monitor SpO₂ readings as desaturation occurs and is followed by reoxygenation. The study focuses on the timing and accuracy of peripheral pulse oximetry signals in reflecting true arterial oxygen levels during rapid desaturation and subsequent resaturation. The goal is to understand whether SpO₂ displays delays that could affect clinical decisions during airway management or procedural sedation. No disease intervention is tested; the study examines measurement performance under controlled, healthy conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy adult volunteers aged 18 to 60 years
* Able to perform voluntary apnea for at least 30 seconds
* Written informed consent, read and signed by the participant

Exclusion Criteria:

* History of chronic respiratory, cardiac, or hematological disease
* Recent respiratory infection (\< 2 weeks)
* Use of vasoactive medications (e.g., beta-blockers, vasodilators)
* Known or suspected pregnancy
* Inability to understand the study information or follow the study instructions
* Refusal to participate or withdrawal of consent

Where it's running

• Cliniques Universitaires Saint-Luc
  Brussels, Belgium Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.