Improving breathing in children with orthodontic treatment
Skeletal, Dental and Upper Airway Changes in Skeletal Class II Division 1 Patients With the Constricted Maxilla (8-14 Years Old) Treated With Twin Block and Hyrax, Evaluated Through Pressure Drop Experimental Analysis.
This study is testing if certain orthodontic treatments can help children with breathing problems by improving their airway size and making it easier to breathe.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 8 Years to 14 Years |
| Sex | All |
| Sponsor | University of Alberta Academic / other |
| Locations | 1 site (Edmonton, Alberta) |
| Trial ID | NCT04190953 on ClinicalTrials.gov |
What this trial studies
This research investigates how orthodontic treatments, specifically mandibular advancement and maxillary expansion, can enhance upper airway volume and reduce respiratory effort in children with class II malocclusion. The study will analyze changes in airway dimensions and airflow resistance using a randomized crossover controlled trial design involving 90 children aged 8-14. Participants will be divided into groups receiving different treatment sequences, and their respiratory capabilities will be assessed using portable polysomnography. The goal is to establish a correlation between orthodontic interventions and improved breathing outcomes.
Who should consider this trial
Good fit: Ideal candidates are children aged 8-14 with skeletal class II division 1 malocclusion and maxillary constriction.
Not a fit: Patients with syndromic conditions, previous orthodontic treatment, or severe oral health issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved breathing and reduced respiratory issues in children undergoing orthodontic treatment.
How similar studies have performed: Previous studies have indicated a positive relationship between orthodontic interventions and airway improvements, suggesting this approach has potential based on existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * children between the ages 8-14 years old (8-12 years old girls and 9-14 years old boys), presenting skeletal class II division 1 malocclusion with maxillary constriction Exclusion Criteria: * syndromic patients, previous ortho history, non-compliance, severe oral health issues (cavities, poor oral hygiene)
Where this trial is running
Edmonton, Alberta
- University of Alberta — Edmonton, Alberta, Canada (Recruiting)
Study contacts
- Principal investigator: Silvia G Capenakas, MSc — University of Alberta
- Study coordinator: Manuel Lagravere, PHD
- Email: manuel@ualberta.ca
- Phone: 7804927696
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.