How pregnancy weight gain affects spinal anesthesia during a planned cesarean
Effect of Gestational Weight Gain on Regional Anesthesia in Cesarean Patients
This project will see if the amount of weight a pregnant person gains changes how spinal anesthesia works for women having an elective C-section.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | Elazıg Fethi Sekin Sehir Hastanesi Academic / other |
| Locations | 1 site (Elâzığ, Elaziğ) |
| Trial ID | NCT07326644 on ClinicalTrials.gov |
What this trial studies
This is a prospective, observational, non-interventional study conducted at Fethi Sekin City Hospital in Elâzığ, Turkey. Pregnant women scheduled for elective cesarean delivery under spinal anesthesia will be enrolled and grouped by gestational weight gain according to the 2009 IOM guidelines. Study staff will record spinal block characteristics, intraoperative hemodynamic responses (such as blood pressure and heart rate), and routine perioperative outcomes using standard clinical care data. No extra procedures, medications, or interventions beyond routine care will be performed.
Who should consider this trial
Good fit: Pregnant women aged 18–45 with a single, term pregnancy scheduled for elective cesarean under spinal anesthesia who have documented pre-pregnancy and pre-delivery weights are ideal candidates.
Not a fit: People with preeclampsia, diabetes, multiple pregnancy, preterm delivery, morbid obesity (BMI ≥45), fetal anomalies, or who require conversion to general anesthesia were excluded and are unlikely to benefit from these results.
Why it matters
Potential benefit: If successful, the findings could help anesthesiologists personalize spinal anesthesia planning and monitoring based on how much weight a patient gained during pregnancy to improve safety and comfort.
How similar studies have performed: Prior research indicates maternal BMI and body habitus can affect spinal block spread and blood pressure responses, but direct evidence specifically linking IOM gestational weight gain categories to cesarean spinal anesthesia characteristics is limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pregnant women aged 18-45 years * Single pregnancy * Planned elective cesarean section * Spinal anesthesia (regional anesthesia technique) * Pre-pregnancy weight information available (maternal health record, e-Nabız or file record) * Recorded pre-delivery weight information * Gestational weight gain (GWG) calculable according to the IOM 2009 classification * ASA I-II pregnant women * Voluntary participation in the study and informed consent Exclusion Criteria: * Pregnant women with preeclampsia, severe preeclampsia, eclampsia, or HELLP syndrome * Pregnant women with a history of gestational diabetes or pregestational diabetes * Multiple pregnancy (twins, triplets, etc.) * Preterm pregnancy (\<37 weeks) * Failure of spinal anesthesia or need for conversion to general anesthesia * Lack of pre-pregnancy weight information or weight gain data during pregnancy * Pregnancies with fetal anomalies * Morbid obesity (BMI ≥ 45 kg/m²)
Where this trial is running
Elâzığ, Elaziğ
- Fethi Sekin City Hospital — Elâzığ, Elaziğ, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: SAİT F ÖNER, MD, PhD
- Email: sfatihoner@gmail.com
- Phone: +905336271358
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.