How patients' information and expectations affect outcomes after major abdominal cancer surgery

Evaluating Health Literacy, Expectations and Regrets in Patients Undergoing Major Abdominal Surgery for Malignant Disease

Observational Rigshospitalet, Denmark · NCT07450950

This project will see if patients' health literacy and preoperative expectations before major abdominal cancer surgery relate to their later feelings of regret and quality of recovery.

Quick facts

Study typeObservational
Enrollment90 (estimated)
Ages18 Years and up
SexAll
SponsorRigshospitalet, Denmark Academic / other
Locations1 site (Copenhagen, Copenhagen)
Trial IDNCT07450950 on ClinicalTrials.gov

What this trial studies

This prospective observational cohort at Copenhagen University Hospital (Rigshospitalet) will enroll adults scheduled for elective major abdominal cancer surgeries, including pancreatic, hepatic, esophageal, gastric, and major colorectal procedures. Participants complete validated questionnaires on health literacy, preoperative information and expectations at baseline, then again about one month and three months after surgery to capture postoperative experiences, decision regret, and health-related quality of life. Investigators will correlate baseline literacy and expectation measures with postoperative regret and recovery metrics to identify patterns of unmet information needs. No investigational treatments are given; the study uses questionnaire data collected during routine care.

Who should consider this trial

Good fit: Adults (≥18) who can read Danish and are scheduled for elective major abdominal cancer surgery at Rigshospitalet are ideal candidates.

Not a fit: Patients who cannot read Danish, who are cognitively unable to complete questionnaires, or who undergo emergency surgery are unlikely to benefit from participating.

Why it matters

Potential benefit: If successful, the findings could help hospitals improve how they inform and support patients so fewer people experience unexpected outcomes or decision regret after major abdominal cancer surgery.

How similar studies have performed: Prior research has linked lower health literacy and unmet expectations to worse patient-reported outcomes and decision regret in surgical populations, but this study applies those ideas specifically to major abdominal cancer operations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients \> 18 years undergoing elective surgical treatment.
* Patients who can read and understand the Danish language.

Exclusion Criteria:

\- Patients who are cognitively disabled and cannot mentally cooperate with the study design, as assessed by the investigator.

In accordance with the Declaration of Helsinki, patients have the right to withdraw from the study at any time for any reason

Where this trial is running

Copenhagen, Copenhagen

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Surgery, Major PancreaticSurgery, Major HepaticLarge Bowel/Sarcoma ResectionsSurgery, Major Esophageal or StomachHealth literacyPatient expectationsExpectationsDecision
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.