How often the diaphragm is weakened after cesarean delivery in women with severe preeclampsia
Official title: Incidence of Postoperative Diaphragmatic Dysfunction in Pregnant Women With Preeclampsia With Severe Features Undergoing Cesarean Delivery: A Prospective Observational Study
Run by Cairo University · NCT07443345 · Data updated 2026-11-12
We will use ultrasound to see if women with severe preeclampsia develop diaphragm weakness after cesarean delivery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 40 Years |
| Sex | Women only |
| Enrollment | 52 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | March 9, 2026 |
| Main results expected | December 30, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | March 11, 2026 |
| Trial ID | NCT07443345 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 20 or older with severe preeclampsia at gestational age >32 weeks who are scheduled for cesarean delivery and can undergo diaphragmatic ultrasound are the intended participants.
✕Probably not a fit
Patients under 20, people with diabetes or neuromuscular disease, those who refuse participation, or anyone who cannot obtain adequate ultrasound views are excluded and unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study enrolls women with severe preeclampsia at >32 weeks gestation undergoing cesarean delivery at Cairo University Hospitals. Investigators will use bedside ultrasound to measure diaphragmatic function in the perioperative period and record clinical data on comorbidities, anesthesia, and postoperative respiratory outcomes. The primary goal is to determine the incidence of postoperative diaphragmatic dysfunction and to identify perioperative risk factors associated with dysfunction. No experimental treatments are given; the protocol excludes patients under 20, diabetics, those with neuromuscular disease, or anyone who cannot obtain adequate ultrasound views.
Why it matters
Potential benefit: If successful, the findings could help clinicians identify patients at higher risk for postoperative diaphragm weakness and guide monitoring or preventive care to reduce respiratory complications.
How similar studies have gone: Prior research has documented respiratory complications such as pulmonary edema and respiratory failure in preeclampsia, but few studies have specifically measured postoperative diaphragmatic function with objective ultrasound, so this application is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with severe preeclampsia undergoing cesarean section * Gestational age \> 32 weeks Exclusion Criteria: * • Age \< 20 years. * Diabetic * Patients with neuromuscular diseases. * Patient refusal. * Contraindications to magnesium sulphate administration * Inability to obtain adequate ultrasound views
Where it's running
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Cairo University Hospitals
Cairo, Egypt Recruiting
Study contacts
- Study coordinator: Mina Adolf Helmy, MD
- Email: minaadolf1988@cu.edu.eg
- Phone: 01275716942
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.