How eyeliner affects tear composition, tear secretion, and tear film stability

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study compares adults who regularly wear eyeliner with those who do not to look for differences in ocular surface characteristics. Participants complete the Ocular Surface Disease Index questionnaire and undergo tear secretion testing, sodium fluorescein staining, intraocular pressure measurement, and clinical dry-eye analysis. Tears are collected by capillary tube and stored for Raman spectroscopy to identify compositional differences. Clinical and biochemical measures will be compared between the eyeliner and control groups to explore links between eyeliner use and tear film instability.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* People aged 20-35 who use eyeliner or do not use eyeliner .
* People who use eyeliner have used it for ≥ 1 year; Frequency ≥ 3 times/week.

Exclusion Criteria:

* Other serious systemic diseases.
* Other systemic diseases related to ocular surface, such as rheumatoid arthritis, systemic lupus erythematosus, Sjogren's syndrome and other immune system diseases or other eye diseases, history of eye surgery and trauma.
* Lactating women or pregnant women.
* Use electronic products for more than 4 hours every day.
* Patients with circadian rhythm disorder.
* People with radiation exposure history.
* Non permanent residents in Wuhan.

Where it's running

• Zhongnan Hospital of Wuhan University
  Wuhan, Hubei, China Recruiting

Study contacts

• Study coordinator: Min Ke
• Email: keminyk@163.com
• Phone: +86 18672395959

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.