How endobronchial valves change oxygen use during everyday activities

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study of patients scheduled for bronchoscopic lung volume reduction with Pulmonx Zephyr endobronchial valves. Researchers will measure oxygen uptake (VO2) and carbon dioxide production (VCO2) with a portable metabolic device while participants perform typical activities of daily living before and after EBV treatment. The primary focus is to compare the metabolic load and symptom perception during ADLs rather than laboratory walk tests. Results will show whether physiological effort during real-world tasks changes after valve placement.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patient is scheduled for a bronchoscopic lung volume treatment using Pulmonx Zephyr Endobronchial Valves;
2. Patient read, understood and signed the Informed Consent Form.

Exclusion Criteria:

1\) Patients who cannot perform ADL activities without the use of Long Term Oxygen Therapy (LTOT).

Where it's running

• University Medical Center Groningen
  Groningen, Netherlands Recruiting

Study contacts

• Principal investigator: Dirk-Jan Slebos, MD PHD — University Medical Center Groningen
• Study coordinator: Jorine E Hartman, PhD
• Email: j.hartman@umcg.nl
• Phone: 0031503619194

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.