Clinical trial Recruiting at 1 site Observational Ages 18 and up

How CAR-T cell therapy affects fertility

Official title: The Impact of CAR-T Cell Therapy on Fertility; A Patient Survey

Run by Blood Cancer United · NCT07173322 · Data updated 2026-11-12

This survey asks adults with cancer who have received CAR-T therapy about their fertility to see if CAR-T impacts reproductive health.

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Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorBlood Cancer United
Academic / other
Drugs / interventionsCAR-T
Locations1 site (Rye, New York)
StatusRecruiting
StartedFebruary 9, 2025
Main results expectedFebruary 9, 2026
Study endsFebruary 9, 2026
Registry record updatedSeptember 15, 2025
Trial IDNCT07173322 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18 or older with any cancer who have received or are currently receiving CAR-T cell therapy are ideal candidates.

Probably not a fit

People under 18, individuals who have never had CAR-T therapy, and those seeking direct fertility treatment rather than survey participation are unlikely to benefit from this survey.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational patient survey led by Blood Cancer United with University of Florida collaboration that collects self-reported fertility and reproductive-history information from adults who received CAR-T cell therapy. Participants complete an online questionnaire about menstrual function, sexual health, pregnancies, sperm/egg preservation, and timing relative to CAR-T treatment. No experimental interventions are given; data will be analyzed to identify patterns and inform clinical guidance. The findings aim to fill gaps in knowledge about CAR-T–related reproductive effects and guide future fertility preservation strategies.

Why it matters

Potential benefit: If successful, results could help clinicians give better fertility counseling and shape preservation options for patients considering or receiving CAR-T therapy.

How similar studies have gone: Specific data on CAR-T effects on fertility are limited, so this survey is relatively novel though fertility impacts of other cancer therapies have been previously studied.

Who can join: the full rules

Show full inclusion / exclusion criteria
* any cancer patient
* at least 18 years of age
* with a history of receiving CAR-T Cell treatment.

less than 18 years old.

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Where it's running

  • Internet
    Rye, New York, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.