How CAR-T cell therapy affects fertility
Official title: The Impact of CAR-T Cell Therapy on Fertility; A Patient Survey
Run by Blood Cancer United · NCT07173322 · Data updated 2026-11-12
This survey asks adults with cancer who have received CAR-T therapy about their fertility to see if CAR-T impacts reproductive health.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Blood Cancer United Academic / other |
| Drugs / interventions | CAR-T |
| Locations | 1 site (Rye, New York) |
| Status | Recruiting |
| Started | February 9, 2025 |
| Main results expected | February 9, 2026 |
| Study ends | February 9, 2026 |
| Registry record updated | September 15, 2025 |
| Trial ID | NCT07173322 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older with any cancer who have received or are currently receiving CAR-T cell therapy are ideal candidates.
✕Probably not a fit
People under 18, individuals who have never had CAR-T therapy, and those seeking direct fertility treatment rather than survey participation are unlikely to benefit from this survey.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational patient survey led by Blood Cancer United with University of Florida collaboration that collects self-reported fertility and reproductive-history information from adults who received CAR-T cell therapy. Participants complete an online questionnaire about menstrual function, sexual health, pregnancies, sperm/egg preservation, and timing relative to CAR-T treatment. No experimental interventions are given; data will be analyzed to identify patterns and inform clinical guidance. The findings aim to fill gaps in knowledge about CAR-T–related reproductive effects and guide future fertility preservation strategies.
Why it matters
Potential benefit: If successful, results could help clinicians give better fertility counseling and shape preservation options for patients considering or receiving CAR-T therapy.
How similar studies have gone: Specific data on CAR-T effects on fertility are limited, so this survey is relatively novel though fertility impacts of other cancer therapies have been previously studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
* any cancer patient * at least 18 years of age * with a history of receiving CAR-T Cell treatment. less than 18 years old. \-
Where it's running
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Internet
Rye, New York, United States Recruiting
Study contacts
- Principal investigator: Nina Logan, MD — The Leukemia and Lymphoma Society
- Study coordinator: Janaela Scott
- Email: Janaela.Scott@lls.org
- Phone: 844-696-7228 (24 hours)
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.