Home-based exercise to maintain strength and mobility during cancer treatment for adults 60 and older
Effects of a Multicomponent Exercise Program on Functional Capacity, Neuromuscular Parameters, Quality of Life, and Disease-Related Symptoms in Older Adults Undergoing Cancer Treatment: A Randomized, Controlled Clinical Trial
This trial tests whether a year-long, home-based multicomponent exercise program helps adults aged 60 and older who are receiving cancer treatment stay stronger, move better, and feel better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 180 (estimated) |
| Ages | 60 Years and up |
| Sex | All |
| Sponsor | Federal University of Rio Grande do Sul Academic / other |
| Locations | 2 sites (Porto Alegre, Rio Grande do Sul and 1 other locations) |
| Trial ID | NCT07565519 on ClinicalTrials.gov |
What this trial studies
This randomized controlled trial will compare a one-year, home-based multicomponent exercise program based on the ViviFrail model to usual care in older adults undergoing cancer treatment. Participants will be assessed at baseline and after 12, 24, and 48 weeks for walking speed, balance, muscle strength, quality of life, symptoms, and daily activity. The program is delivered for home use with exercises tailored to older adults and safety oversight, while the control group continues routine care. The study enrolls men and women aged 60 or older treated at Hospital Conceição in Porto Alegre who can walk and have medical clearance to exercise.
Who should consider this trial
Good fit: Men and women aged 60 years or older receiving cancer treatment at Hospital Conceição who can walk (with or without assistance), understand exercise instructions, and have medical clearance to participate are ideal candidates.
Not a fit: Patients who are non-ambulatory, lack the cognitive ability to follow the exercises, miss required assessments, or have medical contraindications to exercise may not receive benefit.
Why it matters
Potential benefit: If successful, the program could help older adults on cancer treatment preserve physical function, reduce symptoms, and maintain independence.
How similar studies have performed: Similar multicomponent and home-based exercise programs have improved strength, mobility, and quality of life in older adults and cancer survivors, though evidence specifically during active cancer treatment is more limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Men and women aged 60 years or older who are undergoing cancer treatment at Hospital Conceição in Porto Alegre, who have the cognitive ability to understand the exercises, are able to walk (even with assistance), and have medical clearance to participate in physical exercise will be included in the study. \- Exclusion Criteria: Participants who miss more than two assessments will be excluded. \-
Where this trial is running
Porto Alegre, Rio Grande do Sul and 1 other locations
- Escola de Educação Física Fisioterapia e Dança - UFRGS — Porto Alegre, Rio Grande do Sul, Brazil (Not_yet_recruiting)
- Hospital Conceição — Porto Alegre, Brazil (Recruiting)
Study contacts
- Principal investigator: Eduardo L Cadore, PhD — Federal University of Rio Grande do Sul
- Study coordinator: Eduardo L Cadore, PhD
- Email: edcadore@yahoo.com.br
- Phone: +555191193651
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.