Home-based exercise and protein counselling to prevent frailty in the elderly

EPPIC Trial: Exercise Program and Protein Intake Counselling for Frailty Prevention in Singapore

Not applicable Interventional National Healthcare Group Polyclinics · NCT06418425

This study is testing if a home exercise program and protein advice can help older adults at risk of frailty in Singapore stay healthier.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment240 (estimated)
Ages65 Years to 100 Years
SexAll
SponsorNational Healthcare Group Polyclinics Government
Locations1 site (Singapore, Singapore)
Trial IDNCT06418425 on ClinicalTrials.gov

What this trial studies

This randomized controlled trial investigates the effectiveness of a home-based exercise program combined with dietary protein counselling aimed at preventing frailty among elderly individuals in Singapore's primary care setting. Participants aged 65 to 100 years old, identified as having pre-frailty, will be randomly assigned to either the intervention group receiving the exercise and dietary counselling or a usual care group. The study will involve initial screening by care coordinators, followed by physical consultations for eligible participants to obtain consent and further details. The goal is to assess whether this combined approach can improve health outcomes in this vulnerable population.

Who should consider this trial

Good fit: Ideal candidates are elderly individuals aged 65 to 100 years who are community-dwelling and have been identified as pre-frail.

Not a fit: Patients with significant medical conditions limiting their physical activity or dietary changes, as well as those already receiving similar interventions, may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce the incidence of frailty among the elderly, improving their overall health and quality of life.

How similar studies have performed: Other studies have shown promising results with similar interventions combining exercise and dietary modifications for frailty prevention, indicating a potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 65 - 100 years old
* Community dwelling
* On chronic disease follow up with polyclinic
* Ability to communicate in English or Mandarin
* Able to understand the study and give consent

Exclusion Criteria:

* Individuals with existing dietitian/ physiotherapy intervention (Individuals who are already seeing dietitian for special delivery requirements, or seeing physiotherapist for musculoskeletal exercises for specific condition or injury)
* Institutionalized individuals
* Individuals with significant medical conditions limiting their physical activity or high protein diet, such as severe heart conditions, recent strokes, active malignancy, chronic kidney disease stage 3-5 etc.
* Terminal illness with life expectancy \< 12 months
* severe audiovisual impairment
* Not able to communicate in English or Mandarin
* Pregnant women ( as population involves participants beyond childbearing age, investigators do not expect to include pregnant women in this study)

Where this trial is running

Singapore, Singapore

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Frailtyfrailtypre-frailtyprimary careexercisehigh protein dietnutrition
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.