Hip fracture thrombosis prevention: aspirin vs LMWH after surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The DIRECT study tests two common ways to prevent clots in people who have had a hip fracture. It compares aspirin taken by mouth to low molecular weight heparin given as injections, in a randomized crossover design. Participants are adults aged 60 to 150 with fragility hip fractures and are enrolled through UK hip fracture registries. The trial aims to determine which approach is safer and more effective for thromboprophylaxis in this setting. Lead sponsorship is by Queen Mary University of London, with study sites including Whipps Cross University Hospital in London.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults from 60 to 150 years sustaining fragility hip fracture identified by their entry into UK hip registries.

Exclusion Criteria:

* Individuals who do not meet the eligibility criteria to be enrolled in the NHFD and SHFA registries Hip fracture individuals above 150 years of age.

Where it's running

• Whipps Cross University Hospital
  London, United Kingdom Recruiting

Study contacts

• Study coordinator: Nkemjika S Abiakam, BSc, MRes, MSc, PhD
• Email: n.abiakam@qmul.ac.uk
• Phone: 00000000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.