HIIT versus time-restricted eating to lower type 2 diabetes risk in adolescents and young adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial enrolls adolescents (14–17 years with BMI percentile ≥85th) and young adults (18–30 years with BMI ≥25 kg/m2) with overweight or obesity and randomly assigns them to a 4-week high-intensity interval training (HIIT) program or a time-restricted eating (TRE) schedule. The primary outcomes are changes in cardiometabolic biomarkers measured before and after the intervention, such as insulin sensitivity, blood lipids, and other metabolic indicators. Participants with major chronic medical conditions or on excluded medications are not eligible, and interventions are delivered at Syracuse University with close monitoring. The design focuses on short-term physiological responses to lifestyle changes that are feasible for adolescents and young adults.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adolescents (age 14-17 years old with sex- and race-specific BMI percentile ≥85th) and young adults with overweight and obesity (age 18 to 30 years old with BMI ≥25 kg/m2)

Exclusion Criteria:

* Chronic medical conditions: heart disease, arrhythmias, diabetes, thyroid disease, bleeding disorder, history of pulmonary disease, hypertension, hepatorenal disease, musculoskeletal disorder, neuromuscular/neurological disease, autoimmune disease, cancer, peptic ulcers, anemia, or chronic infection (HIV).
* Have taken any heart, pulmonary, thyroid, anti-hyperlipidemic, hypoglycemic, anti- hypertensive, endocrinologic (e.g., thyroid, insulin, etc.), emotional/psychotropic (e.g., Prednisone, Ritalin, Adderall), neuromuscular/neurological, or androgenic medications (anabolic steroids).
* Have a pacemaker.

Where it's running

• Syracuse University
  Syracuse, New York, United States Recruiting

Study contacts

• Study coordinator: Wonhee Cho, MS, PhD Candidate
• Email: wcho02@syr.edu
• Phone: +16267270270

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.