Clinical trial Recruiting at 2 sites Interventional Ages 18 and up

High-intensity laser treatment for upper-trapezius trigger point pain

Official title: Effectiveness of High Intensity Laser Therapy (HILT) and Stretching Exercises on Cervical Flexibility and Pain Reduction in Myofascial Trigger Points. Randomized Clinical Trial (RCT).

Run by Quiropraxia y Equilibrio · NCT04445545 · Data updated 2026-11-12

We will test whether high-intensity laser therapy, compared with fake laser or ultrasound plus stretching, reduces neck trigger point pain and improves neck movement in university students and staff.

More Trigger Point Pain, Myofascial trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment24 (estimated)
SponsorQuiropraxia y Equilibrio
Academic / other
Locations2 sites (Santiago, Las Condes and 1 other locations)
StatusRecruiting
StartedMay 1, 2025
Main results expectedSeptember 1, 2025
Study endsSeptember 1, 2025
Registry record updatedAugust 7, 2025
Trial IDNCT04445545 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) who are students or staff at Universidad Andrés Bello with latent myofascial trigger points in a shortened upper trapezius and no recent neck or shoulder pathology.

Probably not a fit

People with recent neck/shoulder injuries, implanted metal near the area, skin lesions, photosensitivity, neurological deficits, or chronic use of analgesics/anti-inflammatories/muscle relaxants are excluded and unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized clinical trial will recruit adult students and staff at Universidad Andrés Bello who have latent myofascial trigger points in the upper trapezius. Participants are randomly assigned to one of three groups: high-intensity laser therapy (HILT) plus stretching, sham HILT plus stretching, or therapeutic ultrasound plus stretching, with treatments twice weekly for four weeks. Main outcomes — pain intensity, pain pressure threshold, cervical range of motion, and neck disability — are measured at baseline, during treatment, and at post-treatment follow-up. The sample size was calculated for 85% power using an expected moderate effect size based on prior PPT differences in MTrP research.

Why it matters

Potential benefit: If successful, HILT could offer a noninvasive option to reduce trigger point pain and improve neck mobility.

How similar studies have gone: Previous small trials of high- and low-level laser therapies for myofascial pain have shown some pain and pressure-sensitivity improvements, but the evidence is limited and inconsistent.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants over 18 years of age.
* Officials and students of the Casona las Condes Campus of the Andrés Bello University.
* Presence of myofascial trigger points in the shortened upper trapezius muscle evaluated (expert consensus establishing criteria for the diagnosis of MTrPs, Delphi study).25

Exclusion Criteria:

* Musculoskeletal problems or pathologies of the neck or shoulders in the last 3 months (fractures, sprains, tendinopathies, dislocations, or muscle tears).
* Presence of osteosynthesis materials near shoulders, neck, or surrounding areas.
* Presence of wounds or skin changes in the shoulder and/or neck region (such as psoriasis, scars, or burns).
* Use of analgesic, anti-inflammatory, or muscle relaxant medications for permanent use.
* Neurological changes such as paresthesia, loss of sensitivity (partial or complete), decreased strength, and color changes in the neck, arms, forearms, or hands.
* Diagnosed photosensitivity.
* Presence of solar urticaria or adverse reactions to sunlight.
* Presence of the following conditions: dermatomyositis, systemic lupus erythematosus, hepatic porphyria, cutaneous carcinoid syndrome or pellagra
* Cancer or tumors of any type diagnosed.
* Epilepsy.

Where it's running

  • Universidad Andrés Bello
    Santiago, Las Condes, Chile
    Recruiting
  • Universidad Andrés Bello
    Santiago, Santiago Metropolitan, Chile
    Recruiting

Study contacts

  • Principal investigator: Hernán A de la Barra Ortiz, Mg — Universidad Nacional Andres Bello
  • Study coordinator: Hernán A De la Barra Ortiz, Mg.
  • Email: hdelabarra@unab.cl
  • Phone: 984706322

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.