High-Intensity Interval Training for Depression in Older Adults

Effects of High-Intensity Interval Training on Depressive Symptoms in Hong Kong Older Adults With Mild and Moderate Depression: A Cluster-Randomized Controlled Trial

Not applicable Interventional Hong Kong Baptist University · NCT06014294

This study is testing if high-intensity interval training can help older adults in Hong Kong feel less depressed compared to other activities like Qigong and recreation workshops.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment144 (estimated)
Ages60 Years to 74 Years
SexAll
SponsorHong Kong Baptist University Academic / other
Locations1 site (Hong Kong)
Trial IDNCT06014294 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of high-intensity interval training (HIIT) on depressive symptoms among older adults in Hong Kong. It employs a cluster randomized controlled trial design with three groups: one receiving HIIT, another practicing Baduanjin Qigong, and a third participating in a recreation workshop. Participants will be assessed at baseline, immediately post-intervention, and three months later on various outcomes including depressive symptoms, cortisol levels, sleep quality, quality of life, and physical fitness. The aim is to determine if HIIT can provide a more effective alternative to traditional moderate-intensity exercise for this population.

Who should consider this trial

Good fit: Ideal candidates are Chinese older adults aged 60 to 74 with mild to moderate depressive symptoms and no cognitive impairment.

Not a fit: Patients with severe chronic diseases that restrict high-intensity exercise or those with cognitive impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve mental health and quality of life for older adults suffering from depression.

How similar studies have performed: While traditional moderate-intensity exercise has shown benefits for older adults with depression, the effectiveness of HIIT in this demographic is less established, making this a novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 60 to 74 years at the start date of the project
* Chinese version of Geriatric Depression Scale (GDS-C) scoring 5-11 (i.e., mild to moderate level of depressive symptoms)
* Passing the PAR-Q plus screening or with the physician's approval for readiness to participate in high-intensity exercise
* Above the average level of 2-mins stepping showing competent aerobic fitness
* No restriction on physical mobility
* No cognitive impairment, as determined by the Chinese version of the Mini-Mental Status Examination (i.e., score \< 24)
* No previous substantial experiences in practicing HIIT or Baduanjin Qigong. The written informed consent form will be collected from each participant

Exclusion Criteria:

* Severe chronic disease restricting high-intensity exercise
* Having cognition impairment regarded by specialists

Where this trial is running

Hong Kong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Depressive SymptomsDepressive symptomsOlder adultsHigh-intensity interval trainingBaduanjin Qigong
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.