High-definition surface electromyography to diagnose and monitor sarcopenia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter, descriptive, cross-sectional, parallel-group study plans to enroll 846 patients aged 75 and over hospitalized in acute geriatric or rehabilitation wards who screen positive for sarcopenia (SARC-F ≥4). Investigators will record HD-sEMG signals and extract features to develop diagnostic markers, alongside quadriceps ultrasound, body composition by bioelectrical impedance (and DEXA when available), grip strength, and the IPAQ physical activity questionnaire. Inclusion is planned over 18 months with an additional 3-month follow-up, and the team aims to build an automatic procedure combining functional and morphological muscle data. The study is coordinated by Assistance Publique–Hôpitaux de Paris across multiple AP-HP hospital sites.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient aged 75 years and over
* Score ≥4 on the SARC-F screening questionnaire
* Enrolled in a social security plan (no AME)
* Informed and consenting patient

Exclusion Criteria:

* BMI ≥30 kg/m2
* Severe psychiatric pathology or severe cognitive disorders that do not allow the performance of examinations
* Patients who are dependent for all acts of daily life
* Patients with a very short life expectancy \<3months
* Pace maker
* Recent fracture or trauma of the preventing dynamic measurement of HD-sEMG recording
* Bilateral hip prosthesis
* Skin problem that may interfere with the recording of surface EMG activity
* Skin allergies to plasters
* Allergies to electrode materials (acrylate)
* Patient under legal protection
* Patient on state medical aid (AME : Aide Médicale d'Etat)

Where it's running

• Hôpital Corentin Celton, APHP
  Issy-les-Moulineaux, France Recruiting
• Hôpital Corentin Celton, APHP
  Issy-les-Moulineaux, France Recruiting
• Hôpital Charles Foix, APHP
  Ivry-sur-Seine, France Recruiting
• Hôpital Charles Foix, APHP
  Ivry-sur-Seine, France Recruiting
• Hôpital Charles Foix, APHP
  Ivry-sur-Seine, France Recruiting
• Hôpital Rothschild, APHP
  Paris, France Recruiting

Study contacts

• Study coordinator: Kiyoka KINUGAWA, Prof. MD PhD
• Email: kiyoka.kinugawa@aphp.fr
• Phone: +331 49 59 47 53

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.