Heparin-binding protein and lung edema in ICU patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center observational cohort will enroll about 25 adult ICU patients who are monitored with a PiCCO hemodynamic surveillance device. Researchers will collect blood samples to measure heparin-binding protein (HBP) and record PiCCO-derived measures such as extravascular lung water (EVLW), pulmonary blood volume (PBV), and the pulmonary vascular permeability index (PVPI). They will also track patients' cumulative fluid balance and relevant clinical data. The study will analyze correlations between plasma HBP concentrations and measures of lung vascular permeability, lung water, and total fluid balance.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients \>18 years
* Monitored with a PiCCO system

Exclusion Criteria:

• Patients transferred from another ICU

Where it's running

• ICU
  Östersund, Sweden Recruiting

Study contacts

• Study coordinator: Line Samuelsson, MD
• Email: line.samuelsson@regionjh.se
• Phone: 063153000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.