Clinical trial Recruiting at 1 site Observational Ages 18 and up

Hemoadsorption Therapy in Critically Ill Adults

Official title: Hemodynamic, Laboratory, and Clinical Outcomes of Hemoadsorption theraPy: an obsErvational Study at Flór Ferenc Hospital Using Longitudinal Data (HOPE-FUL)

Run by Pest County Flór Ferenc Hospital · NCT07679555 · Data updated 2026-11-12

This study looks at whether adding CytoSorb or Efferon LPS hemoadsorption after starting vasopressors helps stabilize critically ill adults in Hungary.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment60 (estimated)
SponsorPest County Flór Ferenc Hospital
Academic / other
Locations1 site (Kistarcsa, Pest County)
StatusRecruiting
StartedJanuary 1, 2020
Main results expectedMay 31, 2026
Study endsSeptember 30, 2026
Registry record updatedJuly 7, 2026
Trial IDNCT07679555 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults over 18 years who received CytoSorb or Efferon LPS hemoadsorption with available pre- and post-treatment data.

Probably not a fit

Patients lacking key data or who did not receive the specified hemoadsorption devices may not show benefit in this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-center retrospective observational study conducted at Flór Ferenc Hospital in Kistarcsa, Hungary. It analyzes adult ICU patients who received CytoSorb or Efferon LPS hemoadsorption between January 1, 2020 and May 31, 2026. The researchers will compare pre- and post-treatment data on vasopressor needs, hemodynamics, inflammatory and liver biomarkers, tissue perfusion, and oxygenation, and will report ICU length of stay as well as ICU, 28-day, and 90-day mortality. No interventions are performed as part of the study; data are collected from anonymized medical records. The goal is to clarify how hemoadsorption might affect outcomes in septic shock and other hyperinflammatory states.

Why it matters

Potential benefit: If positive, results could help define when hemoadsorption might benefit critically ill patients and guide clinical decision-making.

How similar studies have gone: Previous studies on hemoadsorption have shown mixed results, making further data in real-world settings valuable but not yet definitive.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* \>18 years;
* CytoSorb or Efferon LPS hemoadsorption treatment,
* with available relevant pre- and post-treatment clinical and laboratory data

Exclusion Criteria:

* age under 18 years
* missing key demographic or outcome data;
* unknown treatment type or timing;
* data unavailable for legal or ethical reasons.

Where it's running

  • Pest County Flór Ferenc Hospital, Dept. of Anaesthesiology and Intensive Therapy
    Kistarcsa, Pest County, Hungary
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.