Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Helping young people who inject drugs start treatment for Hepatitis C

Official title: A Randomized Trial to Test the Efficacy of a Partner Navigation Intervention for HCV Treatment Among Young Adult People Who Inject Drugs

Run by University of California, San Francisco · NCT06179498 · Data updated 2026-11-12

This study tests a new support program to help young adults who inject drugs start treatment for Hepatitis C and see if it works better than regular care.

More Hepatitis C trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorUniversity of California, San Francisco
Academic / other
Locations1 site (San Francisco, California)
StatusRecruiting
StartedMarch 25, 2024
Main results expectedMarch 1, 2027
Study endsJune 1, 2027
Registry record updatedMarch 13, 2025
Trial IDNCT06179498 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are young adults aged 18-30 who have recently been diagnosed with Hepatitis C and have a primary injecting partner.

Probably not a fit

Patients who do not inject drugs or those who are not recently diagnosed with Hepatitis C may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates a behavioral intervention designed to increase the initiation of Hepatitis C treatment among young adults who inject drugs. It involves a randomized controlled trial with 250 participants, including individuals diagnosed with Hepatitis C and their primary injecting partners. The intervention consists of two sessions aimed at providing support and resources to encourage treatment initiation, compared to standard care. The study focuses on young people aged 18-30 to address a critical gap in treatment uptake within this population.

Why it matters

Potential benefit: If successful, this intervention could significantly improve treatment initiation rates for Hepatitis C among young people who inject drugs.

How similar studies have gone: Other studies have shown that behavioral interventions can effectively improve treatment uptake in similar populations, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Self report injecting drugs in the past month
* Self report a primary injecting partner (currently inject drugs together)
* HCV infection identified at partnering community-based clinical site

Where it's running

  • University of California, San Francisco
    San Francisco, California, United States
    Recruiting

Study contacts

  • Principal investigator: Meghan D Morris, MPH, PhD — University of California, San Francisco
  • Study coordinator: Meghan D Morris, MPH, PhD
  • Email: meghan.morris@ucsf.edu
  • Phone: 415-574-0651

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Glecaprevir/pibrentasvir started during pregnancy for women with hepatitis C, with or without HIV

    This trial will test whether taking glecaprevir/pibrentasvir during pregnancy is safe and how the drug is processed in pregnant women who have hepatitis C, including those who also have HIV, and will follow their infants for 10 weeks after birth.

    Recruiting at 8 sites Phase 1/2 National Institute of Allergy and Infectious Diseases (NIAID) · Los Angeles, California and 9 other locations · NCT07040319

  • Evaluating hepatitis C treatment during pregnancy

    This study tests how well a new hepatitis C treatment works for pregnant adults with a history of drug use and looks at their experience during the treatment.

    Recruiting at 2 sites Washington University School of Medicine · St Louis, Missouri and 1 other locations · NCT06367465

  • Decentralized treatment for hepatitis C in Brazil

    This study is testing a new way to treat hepatitis C in Brazil using a medication called Epclusa to see if it helps more people get the care they need compared to traditional methods.

    Recruiting at 2 sites Phase 4 Oswaldo Cruz Foundation · Rio de Janeiro, Rio de Janeiro and 1 other locations · NCT06306300

  • Simplified hepatitis C testing with same-day treatment for people who inject drugs in Armenia, Georgia and Tanzania

    This project will test whether a simplified pathway that starts hepatitis C treatment the same day after a quick antibody test helps people who inject drugs in Armenia, Georgia, and Tanzania get treated and cured faster than the usual antibody-plus-RNA pathway.

    Recruiting Early Phase 1 Médecins du Monde · Yerevan · NCT06159504

  • Point-of-care testing program for Hepatitis C screening

    This study is testing if quick Hepatitis C tests done during a single visit can help more at-risk adults get diagnosed and start treatment faster.

    Recruiting at 6 sites Kirby Institute · Canberra, Australian Capital Territory and 12 other locations · NCT05713136

  • Screening for hepatitis B, hepatitis C and HIV using a dried blood spot

    This project will try a simple dried blood spot test to check people who use drugs for hepatitis B, hepatitis C and HIV.

    Recruiting at 11 sites University Hospital, Rouen · Avranches and 10 other locations · NCT05390424

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.