Helping patients stop smoking before spine surgery

Evaluation of the Influence of Stop Smoking to the Clinical and Radiological Outcome of Instrumented Neck and Back Surgery

NA · Leiden University Medical Center · NCT06361459

This study is testing whether helping patients quit smoking before spine surgery can lead to better recovery and results compared to those who keep smoking or don’t smoke at all.

Quick facts

PhaseNA
Study typeInterventional
Enrollment210 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorLeiden University Medical Center (other)
Locations1 site (Leiden, South Holland)
Trial IDNCT06361459 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the impact of smoking cessation on the clinical and radiological outcomes of patients undergoing moderately complex instrumented spine surgery. It involves a multicenter observational cohort design, comparing outcomes between patients who quit smoking during the peri-operative period, those who continue to smoke, and a control group of non-smokers. Patients will be offered the SineFuma program to assist with quitting, and their progress will be monitored through various assessments over 12 months post-surgery.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 75 who are scheduled for moderately complex instrumented surgery of the neck or low back.

Not a fit: Patients undergoing surgery for malignancy or trauma, as well as non-Dutch speaking individuals and pregnant women, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved recovery and outcomes for patients undergoing spine surgery who quit smoking.

How similar studies have performed: Other studies have shown positive outcomes related to smoking cessation in surgical populations, suggesting this approach may be beneficial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* candidates for moderately complex instrumented surgery of the neck or low back.

Exclusion Criteria:

* Patients undergoing surgery for malignancy or trauma are excluded.
* non Dutch speaking patients
* pregnancy

Where this trial is running

Leiden, South Holland

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Smoking Cessation, smoking cessation, instrumented surgery, spondylodesis

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.