Helping patients stop smoking before spine surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the impact of smoking cessation on the clinical and radiological outcomes of patients undergoing moderately complex instrumented spine surgery. It involves a multicenter observational cohort design, comparing outcomes between patients who quit smoking during the peri-operative period, those who continue to smoke, and a control group of non-smokers. Patients will be offered the SineFuma program to assist with quitting, and their progress will be monitored through various assessments over 12 months post-surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* candidates for moderately complex instrumented surgery of the neck or low back.

Exclusion Criteria:

* Patients undergoing surgery for malignancy or trauma are excluded.
* non Dutch speaking patients
* pregnancy

Where it's running

• Leiden University Medical Centre
  Leiden, South Holland, Netherlands Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Quitting Matters: a smoking quit program for people living with HIV

  This 6-month program will test whether a tailored smartphone app plus nicotine patches and gum helps people living with HIV quit smoking better than a standard quit app.

  Recruiting Wake Forest University Health Sciences · Winston-Salem, North Carolina · NCT06883097

• Smoky Futures: Danish Adolescent Nicotine Use over Time

  This observational cohort follows Danish youths ages 15–25 to see how cigarette, e-cigarette, and other nicotine use begin, change, and affect health and education over several years.

  Recruiting University of Southern Denmark · Copenhagen · NCT07910331

• Nicotine Orodispersible Tablet to Relieve Cravings in Smokers

  A nicotine mint orodispersible tablet is tested vs placebo to see if it quickly eases the urge to smoke in adult cigarette smokers.

  Recruiting Phase 2 Kenvue Brands LLC · Mississauga, Ontario · NCT07893158

• Optimizing when weekly chatbot reminders go out to people using a chatbot for quitting smoking

  This study tests whether sending weekly reminders at different times helps people stay engaged with a chatbot smoking-cessation service.

  Recruiting The University of Hong Kong · Hong Kong · NCT07826884

• NMDA and Sigma-1 combination therapy for smoking cessation with AXS-05

  This phase 3 trial tests whether AXS-05 can help adults quit smoking better than placebo or bupropion.

  Recruiting at 28 sites Phase 3 Axsome Therapeutics, Inc. · Phoenix, Arizona and 27 other locations · NCT07766655

• AI-assisted interactive case-based training to improve smoking cessation counseling by medical interns

  This study tests whether AI-powered interactive case-based training helps medical interns provide better smoking cessation counseling.

  Recruiting Assiut University · Asyut, Assuit · NCT07650721

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.