Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Helping hospitalized heart patients quit smoking

Official title: Remote Smoking Cessation in Hospitalized Cardiac Patients: Bridging the Post-discharge

Run by University of Vermont Medical Center · NCT05738408 · Data updated 2026-11-12

This study is testing if giving financial rewards along with nicotine replacement therapy can help heart patients in the hospital quit smoking for good.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment50 (estimated)
SponsorUniversity of Vermont Medical Center
Academic / other
Locations1 site (Burlington, Vermont)
StatusRecruiting
StartedAugust 12, 2022
Main results expectedJuly 2025
Study endsDecember 2025
Registry record updatedJanuary 20, 2025
Trial IDNCT05738408 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are hospitalized patients over 18 years old who are current smokers and have experienced an acute coronary event.

Probably not a fit

Patients with severe dementia, active malignancies, or those who do not have reliable access to a smartphone may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore new strategies for assisting patients hospitalized due to acute coronary events in quitting smoking. It will evaluate the effectiveness of combining financial incentives with nicotine replacement therapy to promote smoking cessation in this high-risk population. The trial seeks to address the low rates of smoking cessation support provided to cardiac patients during and after hospitalization, which is critical for improving their long-term health outcomes. By focusing on this vulnerable group, the study hopes to enhance adherence to smoking cessation guidelines and reduce the negative health impacts of continued smoking.

Why it matters

Potential benefit: If successful, this approach could significantly improve smoking cessation rates among cardiac patients, leading to better health outcomes.

How similar studies have gone: Other studies have shown promise in using financial incentives and nicotine replacement therapy for smoking cessation, indicating that this approach may be effective.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Patients will be recruited if they:

1. Hospitalization for an acute coronary event which includes myocardial infarction or coronary revascularization (percutaneous intervention or coronary artery bypass)
2. live within 30 miles of UVMMC and are \>18 years of age
3. Current cigarette smoker (defined as reporting any use of cigarettes in the week before admission and \>5 cigarette/day on average over the past 3 months)

Exclusion Criteria:

Patients will be excluded if they have:

1. severe dementia/Alzheimer's disease
2. an active malignancy, excluding non-melanoma skin cancer or low-grade prostate cancer under active surveillance
3. exercise limiting vascular or neuromuscular disease
4. Non-English Speaking
5. No reliable smart-phone
6. Current, regular use of smokeless tobacco or other form of non-combusted tobacco

Where it's running

  • University of Vermont Medical Center
    Burlington, Vermont, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.