Helping hospitalized heart patients quit smoking
Official title: Remote Smoking Cessation in Hospitalized Cardiac Patients: Bridging the Post-discharge
Run by University of Vermont Medical Center · NCT05738408 · Data updated 2026-11-12
This study is testing if giving financial rewards along with nicotine replacement therapy can help heart patients in the hospital quit smoking for good.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | University of Vermont Medical Center Academic / other |
| Locations | 1 site (Burlington, Vermont) |
| Status | Recruiting |
| Started | August 12, 2022 |
| Main results expected | July 2025 |
| Study ends | December 2025 |
| Registry record updated | January 20, 2025 |
| Trial ID | NCT05738408 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are hospitalized patients over 18 years old who are current smokers and have experienced an acute coronary event.
✕Probably not a fit
Patients with severe dementia, active malignancies, or those who do not have reliable access to a smartphone may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to explore new strategies for assisting patients hospitalized due to acute coronary events in quitting smoking. It will evaluate the effectiveness of combining financial incentives with nicotine replacement therapy to promote smoking cessation in this high-risk population. The trial seeks to address the low rates of smoking cessation support provided to cardiac patients during and after hospitalization, which is critical for improving their long-term health outcomes. By focusing on this vulnerable group, the study hopes to enhance adherence to smoking cessation guidelines and reduce the negative health impacts of continued smoking.
Why it matters
Potential benefit: If successful, this approach could significantly improve smoking cessation rates among cardiac patients, leading to better health outcomes.
How similar studies have gone: Other studies have shown promise in using financial incentives and nicotine replacement therapy for smoking cessation, indicating that this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients will be recruited if they: 1. Hospitalization for an acute coronary event which includes myocardial infarction or coronary revascularization (percutaneous intervention or coronary artery bypass) 2. live within 30 miles of UVMMC and are \>18 years of age 3. Current cigarette smoker (defined as reporting any use of cigarettes in the week before admission and \>5 cigarette/day on average over the past 3 months) Exclusion Criteria: Patients will be excluded if they have: 1. severe dementia/Alzheimer's disease 2. an active malignancy, excluding non-melanoma skin cancer or low-grade prostate cancer under active surveillance 3. exercise limiting vascular or neuromuscular disease 4. Non-English Speaking 5. No reliable smart-phone 6. Current, regular use of smokeless tobacco or other form of non-combusted tobacco
Where it's running
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University of Vermont Medical Center
Burlington, Vermont, United States Recruiting
Study contacts
- Study coordinator: Sherrie Khadanga, MD
- Email: sherrie.khadanga@uvmhealth.org
- Phone: 802-847-2700
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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This 6-month program will test whether a tailored smartphone app plus nicotine patches and gum helps people living with HIV quit smoking better than a standard quit app.
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Smoky Futures: Danish Adolescent Nicotine Use over Time
This observational cohort follows Danish youths ages 15–25 to see how cigarette, e-cigarette, and other nicotine use begin, change, and affect health and education over several years.
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Nicotine Orodispersible Tablet to Relieve Cravings in Smokers
A nicotine mint orodispersible tablet is tested vs placebo to see if it quickly eases the urge to smoke in adult cigarette smokers.
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Optimizing when weekly chatbot reminders go out to people using a chatbot for quitting smoking
This study tests whether sending weekly reminders at different times helps people stay engaged with a chatbot smoking-cessation service.
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NMDA and Sigma-1 combination therapy for smoking cessation with AXS-05
This phase 3 trial tests whether AXS-05 can help adults quit smoking better than placebo or bupropion.
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AI-assisted interactive case-based training to improve smoking cessation counseling by medical interns
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.