Helping female childhood cancer survivors with fertility concerns

Addressing Fertility Information Needs and Fertility-related Distress Among Female Adult Survivors of Childhood Cancer

Not applicable Interventional Duke University · NCT06834945

This study is trying out a new program to help female childhood cancer survivors understand their fertility options and feel less anxious about them.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years to 44 Years
SexFemale
SponsorDuke University Academic / other
Locations1 site (Durham, North Carolina)
Trial IDNCT06834945 on ClinicalTrials.gov

What this trial studies

This study aims to develop and refine a behavioral intervention designed to address fertility-related information needs and distress among female adult survivors of childhood cancer. It will utilize a structured approach based on the Obesity-Related Behavioral Intervention Trials (ORBIT) Model, delivering six remote sessions that incorporate patient activation theory and Acceptance and Commitment Therapy (ACT) strategies. The intervention will focus on empowering participants to make informed decisions regarding their fertility by enhancing their knowledge and reducing distress. A small sample of 30 participants will be involved to assess the feasibility and acceptability of the intervention, as well as changes in key outcomes such as fertility health knowledge and psychological flexibility.

Who should consider this trial

Good fit: Ideal candidates for this study are female adult survivors of childhood cancer aged 18-44 who are uncertain about their fertility status.

Not a fit: Patients currently under the care of a fertility specialist or those with major psychiatric concerns may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the fertility-related knowledge and emotional well-being of female survivors of childhood cancer.

How similar studies have performed: While this approach is novel in its specific focus, similar behavioral interventions have shown promise in addressing fertility concerns in other populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Currently aged 18-44
* Diagnosed with cancer at \<18 years old
* Female sex
* Uncertain fertility status

Exclusion Criteria:

* Age \<18
* Currently under the care of a fertility specialist
* Having a major/serious psychiatric concern (e.g., schizophrenia) as indicated by medical chart/medical provider
* Inability to provide consent.

Where this trial is running

Durham, North Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Childhood CancerFertility IssuesFertility ConcernsFertility Distress
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.