Helping Cambodian people with HIV quit smoking using text messages

Ending Tobacco Use Through Interactive Tailored Messaging for Cambodian People Living With HIV/AIDS (Project END-IT)

Not applicable Interventional H. Lee Moffitt Cancer Center and Research Institute · NCT05746442

This study is testing if sending text messages can help people in Cambodia who have HIV quit smoking by providing support and resources.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment800 (estimated)
Ages18 Years and up
SexAll
SponsorH. Lee Moffitt Cancer Center and Research Institute Academic / other
Locations3 sites (Phnom Penh and 2 other locations)
Trial IDNCT05746442 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of an automated text messaging program designed to assist HIV-positive smokers in quitting smoking. Participants will receive tailored messages, nicotine patches, and self-help materials to support their cessation efforts. The program encourages participants to set a quit date within two weeks of enrollment and provides ongoing support through smartphone technology. The study is conducted in collaboration with prominent institutions in Cambodia.

Who should consider this trial

Good fit: Ideal candidates for this study are Cambodian adults aged 18 and older who are HIV-positive and currently smoke cigarettes.

Not a fit: Patients who have medical conditions preventing the use of nicotine replacement therapy or are currently enrolled in other cessation programs may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly improve smoking cessation rates among HIV-positive individuals, enhancing their overall health and quality of life.

How similar studies have performed: Other studies have shown success with text messaging interventions for smoking cessation, indicating a promising approach for this population.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 1\) being aged ≥18 years
* 2\) being HIV-positive
* 3\) self-reporting as a current combustible cigarette smoker (smoked ≥100 cigarettes in lifetime and currently smoke ≥1 cigarettes/day)
* 4\) willing to set a date for a quit attempt within 2 weeks of study enrollment
* 5\) being able to provide written informed consent to participate
* 6\) being able to read Khmer (score ≥4 points on the Rapid Estimate of Adult Literacy in Medicine-Short Form

Exclusion Criteria:

* 1\) history of a medical condition that precludes use of nicotine replacement therapy
* 2\) physician/clinician deemed ineligible to participate based on medical or psychiatric condition
* 3\) enrolled in another cessation program or use of other cessation medications.

Where this trial is running

Phnom Penh and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Smoking CessationHIV
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.