Heart rate variability biofeedback for recovery after brain injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of heart rate variability biofeedback on individuals with mild traumatic brain injury. Participants will be randomly assigned to either an active biofeedback condition aimed at increasing heart rate oscillations or a sham condition designed to decrease them. The study will measure changes in heart rate variability before and after a 5-week treatment period, as well as recovery following stressors. The goal is to determine if biofeedback can improve heart rate variability and associated physical symptoms in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* At least six months post-injury to account for spontaneous recovery
* Aged 18-55 years
* Fluent in English
* Able to provide informed consent.

Exclusion Criteria:

* Presence of a pacemaker
* Previous self-reported heart attack with hospitalization
* Diagnosed learning disability
* Other neurological difficulties or diagnoses (i.e., stroke, epilepsy)
* Participation in current litigation
* Uncorrected visual impairment.

Where it's running

• Brigham Young University
  Provo, Utah, United States Recruiting

Study contacts

• Study coordinator: Leah D Talbert, MS
• Email: leah.d.whitlow@gmail.com
• Phone: 3343141078

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• PIONEER-Prognosis: Using biomarkers and wearables to forecast recovery after mild traumatic brain injury

  This study tests whether blood biomarkers, health data from records, and wearables can help predict how people recover after a mild traumatic brain injury treated in the emergency department.

  Recruiting at 3 sites University of Michigan · Torrance, California and 4 other locations · NCT07858266

• HBOT to see if it helps cognition and well‑being in first responders with prior brain injury

  This study tests whether 40 hyperbaric oxygen therapy sessions can improve thinking skills and post-concussion symptoms in current or former first responders with a history of brain injury.

  Recruiting Phase 2 Summit Hyperbarics and Wellness · Boise, Idaho · NCT07852728

• Depth Electrode Monitoring after Traumatic Brain Injury

  This study tests adding a depth electrode with continuous brain monitoring during external ventricular drain placement in adults with traumatic brain injury to see if cortical reverberation signals can be tracked safely.

  Recruiting Hennepin Healthcare Research Institute · Minneapolis, Minnesota · NCT07842458

• Understanding growth hormone deficiency after a brain injury in adults

  This observational study tests whether growth hormone deficiency affects quality of life and symptoms in adults with traumatic brain injury and whether GH replacement helps after 12 weeks.

  Recruiting University of Calgary · Calgary, Alberta and 1 other locations · NCT07795736

• Electrical stimulation-assisted exercise for people with lower limb paralysis

  This study tests whether adding electrical stimulation during exercise can improve leg muscle strength and endurance for people with paralysis.

  Recruiting Louis Stokes VA Medical Center · Cleveland, Ohio · NCT07768761

• ZEPU-2000 robotic rehab for arm and leg weakness

  This trial tests whether adding ZEPU-2000A, ZEPU-2000D, and ZEPU-2000E robotic rehabilitation to usual therapy helps adults with arm/leg movement problems from stroke, incomplete SCI, TBI, or related conditions.

  Recruiting Bangladesh Medical University · Dhaka · NCT07749612

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.