Clinical trial Recruiting at 3 sites Interventional

Heart failure prevention for patients with type 2 diabetes

Official title: Evaluation of a Pragmatic NT-ProBNP-based Heart Failure Screening Strategy Among Patients With Type 2 Diabetes: STRONG-DM Study (Screening and Treatment Using Risk-based apprOach With NT-ProBNP Guidance in Diabetes Mellitus

Run by University of Texas Southwestern Medical Center · NCT06593327 · Data updated 2026-11-12

This study tests a new way to help people with type 2 diabetes avoid heart failure by using risk scores and alerts for their doctors to provide better care.

Quick facts

Study typeInterventional
SexAll
Enrollment300 (estimated)
SponsorUniversity of Texas Southwestern Medical Center
Academic / other
Locations3 sites (Dallas, Texas and 2 other locations)
StatusRecruiting
StartedFebruary 10, 2025
Main results expectedDecember 10, 2027
Study endsDecember 15, 2027
Registry record updatedSeptember 29, 2026
Trial IDNCT06593327 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are primary care providers who manage patients with type 2 diabetes.

Probably not a fit

Patients who do not have diabetes or those whose primary care providers do not participate in the study will not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial evaluates a heart failure risk assessment and prevention strategy for patients with type 2 diabetes using clinical risk scores and cardiac biomarkers. Primary care providers will receive notifications through electronic health records when their diabetic patients are identified as high risk for heart failure. The study aims to implement evidence-based preventive therapies and facilitate expert consultations or referrals to specialized programs. The goal is to enhance patient outcomes through proactive management of heart failure risks.

Why it matters

Potential benefit: If successful, this approach could significantly reduce the incidence of heart failure in patients with type 2 diabetes.

How similar studies have gone: Other studies have shown promise in using similar risk assessment and prevention strategies, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Primary Care Provider that sees diabetes patients in clinic

Exclusion Criteria:

* Provider does not see patients with Diabetes

Where it's running

  • University of Texas Southwestern Medical Center
    Dallas, Texas, United States
    Recruiting
  • Parkland Health & Hospital System (PHHS)
    Dallas, Texas, United States
    Recruiting
  • Baylor Scott and White - Health System
    Dallas, Texas, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Differentiating heart disease in autoimmune vs. type 2 diabetes

    This study tests whether adult-onset autoimmune diabetes (AID/LADA) and type 2 diabetes (T2D) differ in how diabetic heart disease develops, using advanced heart imaging in people with AID, T2D, and healthy controls.

    Recruiting University of Roma La Sapienza · Rome, Roma · NCT07911007

  • Using Apple Watch data to predict heart failure outcomes

    This study is testing if data from Apple Watches can help predict heart failure problems and the chances of needing to go back to the hospital for patients with heart failure.

    Recruiting University Medical Center Goettingen · Goettigen, Lower Saxony · NCT06819618

  • Comparing Aortix Device to Diuretics for Acute Heart Failure

    This study is testing whether the Aortix device can help people with acute heart failure who aren't responding to diuretics feel better compared to standard treatment.

    Recruiting at 33 sites Procyrion · Phoenix, Arizona and 49 other locations · NCT05677100

  • Global registry for patients with type 2 diabetes and related conditions

    This study is collecting information from doctors around the world about patients with type 2 diabetes and related health issues to better understand how these conditions are managed and treated.

    Recruiting at 67 sites AstraZeneca · Fortaleza, Ceará and 75 other locations · NCT03549754

  • Acute Blood Flow Restriction Walking in Type 2 Diabetes

    This study tests whether adding blood flow restriction to treadmill walking affects immune cells in adults with type 2 diabetes.

    Recruiting University of British Columbia · Kelowna, British Columbia · NCT07928531

  • Continuous Glucose Monitoring in Type 2 Diabetes Not on Insulin

    This study tests whether using a continuous glucose monitoring system helps people with type 2 diabetes who aren’t using insulin to improve blood sugar control and quality of life.

    Recruiting Medical University of Bialystok · Bialystok · NCT07919236

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.