Healing the palatal donor site after a free gingival graft using a topical steroid

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized controlled trial, 36 adults needing free gingival grafts are randomly assigned to receive either a collagen hemostatic sponge or topical triamcinolone acetonide at the palatal donor site, with all sites covered by a periodontal dressing. Clinical assessments occur on postoperative days 7, 14, and 30 and include epithelialization testing with hydrogen peroxide bubbling, wound healing scoring using the Landry, Turnbull, and Howley index, and scar evaluation with the modified Manchester Scar Scale. Patient-reported outcomes such as postoperative pain, discomfort, analgesic use, and oral health–related quality of life are recorded alongside clinical measures. The study excludes patients with systemic conditions affecting healing, recent corticosteroid use, tobacco use, pregnancy/lactation, prior palatal surgery, active palatal lesions, or known allergies to study materials.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years and older
* Patients presenting with insufficient attached gingiva and/or gingival recession requiring free gingival graft surgery
* Systemically healthy individuals (ASA I)
* Full-mouth plaque score (FMPS) \< 15% and full-mouth bleeding score (FMBS) \< 15% at the time of surgery
* Ability and willingness to provide written informed consent and comply with study procedures

Exclusion Criteria:

* Presence of systemic diseases that may affect wound healing (e.g., diabetes mellitus, immunological disorders)
* Use of systemic corticosteroids, immunosuppressive drugs, or anti-inflammatory medications within the last 3 months
* Current smokers or tobacco users
* Pregnancy or lactation
* History of periodontal surgery at the palatal donor site
* Presence of active infection, ulceration, or pathological lesions at the palatal donor area
* Known allergy or hypersensitivity to corticosteroids, collagen materials, or study-related medications

Where it's running

• Kahramanmaraş Sütçü İmam University
  Kahramanmaraş, Kahramanmaraş, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: esra bozkurt
• Email: dtesrabozkurt@gmail.com
• Phone: +905533618725

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Palatal Shield Technique to Reduce Pain and Improve Healing After Free Gingival Graft

  This randomized trial tests whether a collagen sponge with a protective palatal shield made of flowable resin helps reduce pain and improve healing after free gingival graft harvest.

  Recruiting Cairo University · Cairo, Cairo Governorate · NCT07926516

• Palatal Wound Healing After Free Gingival Graft in Diabetic Patients

  This study tests palatal wound healing after a free gingival graft in adults with and without diabetes to see if diabetes affects healing and what factors are linked to outcomes.

  Recruiting University of Kentucky · Lexington, Kentucky · NCT07500935

• Oral Mucosa Healing After Gum Recession Treatment in Diabetic People

  This study tests how gingival recession treatment heals in people with diabetes compared with people without diabetes.

  Recruiting University of Kentucky · Lexington, Kentucky · NCT07470281

• Preoperative heart pumping power and P-POSSUM surgical risk score

  We will test whether a quick preoperative measure of heart pumping power (cardiac power output) can help predict complications and death after abdominal surgery in people aged 65 and older.

  Recruiting Necmettin Erbakan University · Konya · NCT07454564

• Theravex Oral and Theravex Tissue Care Plus to improve healing after mucogingival surgery

  We will test if applying Theravex Tissue Care Plus during a modified free gingival graft and rinsing with Theravex Oral afterward helps adults with lower-front gum recession heal faster and get better root coverage than a saline placebo.

  Recruiting Universidad Complutense de Madrid · Madrid, Madrid · NCT07430670

• 3D comparison of soft tissue changes after modified versus conventional free gingival grafts

  This trial will try a modified free gingival graft against a conventional free gingival graft in adults with localized lower-front gum recession to see which better preserves soft tissue thickness and volume.

  Recruiting Kahramanmaras Sutcu Imam University · Kahramanmaraş, Kahramanmaraş · NCT07409558

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.