Healing and comfort after taking a gum graft from the palate

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial compares two wound-closure techniques—traditional sutures versus a cyanoacrylate bioadhesive—after epithelialized gingival graft harvesting from the palate. Participants will be followed for postoperative morbidity, clinical healing, patient-reported pain and eating discomfort, bleeding, analgesic use, and three-dimensional soft-tissue volumetric changes. Investigators will also look for correlations between healing dynamics and patient factors such as anatomy, demographics, and surgical variables. The trial is conducted at the Clínica Universitària d'Odontologia, UIC Barcelona, with standardized clinical and imaging assessments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Systemically healthy individuals older than 18 years old;
* Healthy periodontal status according to the AAP/EFP definition;
* Full-mouth plaque (FMPS) and bleeding scores (FMBS) ≤ 20%;
* No history of soft tissue harvesting.

Exclusion Criteria:

* Pregnancy or lactation;
* Self-reported smoking ≥10 cigarettes/day;
* Metabolic diseases that negatively affect soft tissue healing (i.e., diabetes mellitus);
* Any medication that may interfere with wound healing;
* Removable maxillary prostheses;
* Ongoing orthodontic therapy.

Where it's running

• Clínica Universitària d'Odontologia - UIC Barcelona
  Barcelona, Sant Cugat Del Valles, Spain Recruiting

Study contacts

• Study coordinator: Lory Abrahamian, DDS, MSc, PhD Candidate
• Email: lory.abrahamian@uic.es
• Phone: +34722528012

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Nano-biofusion gingival gel to improve palate wound healing after gum grafts

  We will try a nano-biofusion gingival gel (NBF) to see if it speeds healing, reduces pain, and lowers inflammation for adults who have a palatal donor wound after soft tissue gum graft surgery.

  Recruiting King Abdullah University Hospital · Irbid, Irbid Governorate · NCT07330154

• Palatal Shield Technique to Reduce Pain and Improve Healing After Free Gingival Graft

  This randomized trial tests whether a collagen sponge with a protective palatal shield made of flowable resin helps reduce pain and improve healing after free gingival graft harvest.

  Recruiting Cairo University · Cairo, Cairo Governorate · NCT07926516

• Healing the palatal donor site after a free gingival graft using a topical steroid

  This trial will test whether applying topical triamcinolone acetonide to the palatal donor site helps adults having free gingival graft surgery heal faster and with less pain than a standard collagen sponge.

  Recruiting Kahramanmaras Sutcu Imam University · Kahramanmaraş, Kahramanmaraş · NCT07409571

• Active oxygen gel vs hyaluronic acid gel for palatal healing after graft harvest

  This randomized trial tests whether active oxygen gel or hyaluronic acid gel, each used with a protective dressing, improve palatal wound healing after a free gingival graft compared with a standard gelatin sponge dressing.

  Recruiting Suez Canal University · Ismailia, Ismailia Governorate · NCT07683351

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.