Headache registration and follow-up program at Tongji Hospital

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multicenter, prospective observational cohort led by Tongji Hospital that aims to enroll up to 50,000 participants with clinical data and 1,500 participants who provide biological specimens. Initial data collection includes epidemiological information, clinical assessments, imaging, standardized questionnaires, and a 5 ml venous blood sample, with planned multi-omics and biobanking. Participants will be followed for up to 10 years with face-to-face visits in the first three months and annual telephone follow-ups thereafter to record medication use, clinical outcomes, and adverse events. The project will build integrated clinical and multi-omics databases and apply machine-learning and bioinformatics to identify diagnostic markers, drug targets, and precision treatment strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Meeting the diagnostic criteria for headache classification according to the International Classification of Headache Disorders 3rd edition (ICHD-3, 2018) Age between 6-70 years Voluntary participation with consent Good compliance with follow-up and questionnaire surveys

Exclusion Criteria:

* Complex headache etiology, e.g., presence of ≥3 distinct factors causing headache Presence of severe systemic diseases or life expectancy less than 10 years Significant cognitive or psychiatric issues that prevent completion of questionnaire follow-ups and clinical assessments

Where it's running

• Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology
  Wuhan, Hubei, China Recruiting

Study contacts

• Study coordinator: Wensheng Qu Professor, DM PhD
• Email: wsqu@tjh.tjmu.edu.cn
• Phone: +8618971622660

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.