HBVCare: See if a mobile app helps adults with chronic hepatitis B stick to treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this multicenter randomized trial, adults with chronic hepatitis B in Hanoi use a smartphone app (HBVCare) that provides medication reminders, lab result storage, and health education, to see if it improves treatment adherence over three months compared with standard care. Participants are randomized to either standard care or standard care plus HBVCare, with adherence and related factors measured at three months. The study takes place at Hoang Long Clinic and Hanoi Medical University Hospital and is led by the Institute of Gastroenterology and Hepatology, with Hanoi Medical University as a collaborator. The goal is to identify whether digital health support can reduce barriers to adherence driven by awareness and geographic factors. The app requires smartphone ownership, internet access, and literacy in Vietnamese, and excludes individuals with major cognitive or severe comorbid conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years.
* Diagnosis of Chronic Hepatitis B (CHB): HBsAg (+) and/or HBV DNA positive for ≥ 6 months; Or HBsAg positive and anti-HBc IgM negative.
* Smartphone ownership (iOS or Android) with an active internet connection and the ability to install the HBVCare application.
* Sufficient literacy to read and understand Vietnamese and respond to study questions.
* Provision of informed consent to participate in the study.

Exclusion Criteria:

* Mental health disorders, cognitive impairment, or difficulties in communication and mobile application usage.
* Severe comorbid chronic conditions, such as heart failure, kidney failure, or respiratory failure.
* Presence of severe complications, including gastrointestinal bleeding, liver cancer, hepatic encephalopathy, or acute liver failure.

Where it's running

• Hanoi Medical University Hospital
  Hanoi, Vietnam Recruiting
• Institute of Gastroenterology and Hepatology
  Hanoi, Vietnam Recruiting

Study contacts

• Study coordinator: Trung Quoc Vu
• Email: vuquoctrung0305@gmail.com
• Phone: +84796262002

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.