HbA1c and stomach emptying before anesthesia measured by gastric ultrasound
Evaluation of the Effect of Hemoglobin A1c Levels on Gastric Emptying Assessed by Gastric Ultrasound
This study will test whether adults having elective surgery with higher HbA1c have slower stomach emptying before general anesthesia.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 134 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Kutahya Health Sciences University Academic / other |
| Locations | 1 site (Kütahya, Kütahya) |
| Trial ID | NCT07375680 on ClinicalTrials.gov |
What this trial studies
This prospective observational study will use bedside gastric ultrasonography to measure antral cross-sectional area and estimate gastric volume in adults scheduled for elective surgery after standard fasting. Participants aged 18–70 with ASA physical status I–III will have a preoperative gastric ultrasound performed by trained anesthesiologists and their recent HbA1c values recorded from preoperative labs. Gastric ultrasound measurements and estimated gastric volumes will be compared across different HbA1c levels. Demographic, anthropometric, fasting duration, and clinical data will be collected for secondary analyses exploring factors associated with delayed gastric emptying.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18–70 scheduled for elective surgery under general anesthesia who can provide informed consent and do not have prior gastric surgery or neuromuscular disease.
Not a fit: Patients undergoing emergency surgery, pregnant patients, or those currently using opioids or anticholinergic medications may not benefit from the study or be eligible to participate.
Why it matters
Potential benefit: If successful, the findings could help clinicians better identify patients at higher risk of pulmonary aspiration and tailor anesthetic management based on HbA1c.
How similar studies have performed: Prior studies have linked diabetes and poor long-term glycemic control to delayed gastric emptying, but applying preoperative gastric ultrasound specifically in relation to HbA1c among surgical patients is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Adults aged 18 to 70 years. ASA physical status I-III. Scheduled for elective surgery under general anesthesia. Ability to provide written informed consent. Exclusion Criteria: Scheduled for emergency surgery. Refusal or inability to provide informed consent. Pregnancy. Age \<18 years or \>70 years. History of gastric surgery. Neuromuscular disease. Current use of opioid or anticholinergic medications.
Where this trial is running
Kütahya, Kütahya
- Kutahya Health Science University Training and Research Hospital — Kütahya, Kütahya, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: merve yaman, MD, Assistant Professor — Kutahya Health Science University
- Study coordinator: merve yaman, MD, Assistant Professor
- Email: merve.yaman@ksbu.edu.tr
- Phone: +905363794742
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.