Clinical trial Recruiting at 1 site Interventional Ages 50 and up

Haskap berry supplement for thinking, mood, blood sugar, and blood vessel health in adults 50+

Official title: Investigating the Cognitive, Vascular, and Metabolic Benefits of a Vitamin- and Mineral-Enhanced Haskap Berry Dietary Supplement

Run by University of Reading · NCT07119788 · Data updated 2026-11-12

This will test whether a vitamin- and mineral-enhanced haskap berry supplement can improve thinking, mood, blood sugar responses, and vascular function in healthy adults aged 50 and over after a meal and after 4 weeks of daily use.

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Quick facts

Study typeInterventional
Ages50 Years and up
SexAll
Enrollment90 (estimated)
SponsorUniversity of Reading
Academic / other
Locations1 site (Reading)
StatusRecruiting
StartedJune 19, 2025
Main results expectedFebruary 2026
Study endsApril 2026
Registry record updatedAugust 13, 2025
Trial IDNCT07119788 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are generally healthy adults aged 50 or older with normal BMI, limited fruit and vegetable intake (≤4 servings/day), adequate English and sensory ability for testing, and no major medical conditions or medications that affect outcomes.

Probably not a fit

People with diagnosed cardiometabolic disease (including type II diabetes or cardiovascular disease), untreated hypertension, thrombosis-related disorders, those taking blood thinners, certain dietary restrictions (e.g., vegan/vegetarian), food allergies, or recent antibiotic use are excluded and unlikely to benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will recruit healthy adults aged 50+ and compare a vitamin- and mineral-enhanced haskap powder, pure haskap powder, and a placebo over two in-person testing visits spaced 4 weeks apart. Participants follow a low-polyphenol diet before visits and receive the supplement as part of a meal to measure acute (2-hour) responses and after 4 weeks of daily supplementation to measure chronic effects. Cognitive and mood batteries (memory, executive function, stress), finger-prick blood glucose, and flow-mediated dilation (FMD) for vascular reactivity will be measured at baseline, 2 hours post-meal, and after 4 weeks. The trial compares effects of the enhanced product versus plain haskap powder and placebo to identify any additional cognitive, metabolic, or cardiovascular benefits.

Why it matters

Potential benefit: If successful, this could offer a readily available dietary supplement to modestly improve cognitive performance, mood, blood sugar control, and vascular function in older adults.

How similar studies have gone: Other studies of berry-derived polyphenols have reported some short-term cognitive and vascular benefits but results are mixed and long-term benefits remain unproven, making this vitamin-enhanced haskap formulation relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 50+ years old
* Fruit \& veg intake less than or equal to 4 servings per day
* Adequate English language and visual \& auditory acuity to perform the cognitive tasks
* Normal BMI for age

Exclusion Criteria:

* Being diagnosed with psychological or psychiatric disorders
* ADHD or dyslexia
* Any food allergy or intolerance
* Use of medications and dietary supplements that may impact study results
* Antibiotic use within the last 3 months
* Adherence to vegan or vegetarian diets, or other specific diets that may impact study outcomes
* Conditions altering absorption of nutrients (e.g. celiac disease)
* Being diagnosed with cardiometabolic disease (including type II diabetes and cardiovascular disease), or suffer from untreated hypertension or thrombosis related disorders
* Taking blood thinners

Where it's running

  • Nutrition, Cognition & Health Lab, School of Psychology and Clinical Language Sciences, University of Reading
    Reading, United Kingdom
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.