Hamburg Acute Renal Injury (HARIS) cohort

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

HARIS is a prospective observational cohort enrolling adults hospitalized with acute kidney injury and a parallel control group of hospitalized adults with acute illness who did not develop AKI. An IT-supported screening system flags eligible patients in real time, and participants receive standardized clinical assessments, serial lab testing, and repeated blood and urine biosample collection during hospitalization and at three months after discharge. Biospecimens are processed through a harmonized pipeline and stored in the Hamburg and European Renal Omics-Biobank (HERO) to enable biomarker and omics analyses. Annual structured follow-ups capture long-term outcomes including progression to chronic kidney disease, cardiovascular events, hospital readmissions, and mortality.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Hospitalized individuals with acute kidney injury (AKI), defined by the 2012 Kidney Disease: Improving Global Outcomes (KDIGO) criteria or hospitalized individuals with acute illness who have not developed AKI (control group)
* Age ≥ 18 years at time of enrollment
* Written informed consent provided by the participant or, in participants lacking decision-making capacity, by a legal representative or healthcare proxy, where available. Participants lacking decision-making capacity without an available legal representative or healthcare proxy may be enrolled if participation is not contrary to their presumed wishes, in accordance with the ethics committee-approved consent procedure. Written informed consent is subsequently sought from the participant upon regaining decision-making capacity or from a legal representative, as applicable.

Exclusion Criteria:

* None

Where it's running

• Universitätsklinikum Hamburg-Eppendorf
  Hamburg, Germany Recruiting

Study contacts

• Principal investigator: Tobias B Huber, MD — Universitätsklinikum Hamburg-Eppendorf
• Study coordinator: Christian Schmidt-Lauber, MD
• Email: c.schmidt-lauber@uke.de
• Phone: +49 (0) 40 7410 53908

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.