Gyrotonic exercise for adolescents with lupus who survived intensive care

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial recruits forty adolescents with childhood-onset systemic lupus who recently survived an ICU stay and are at risk for post-ICU syndrome. Participants are randomly assigned to an eight-week Gyrotonic exercise program or a waitlist control group (20 per arm). The study aims to see if the exercise improves fatigue, physical performance, mood, sleep, and quality of life compared with usual care. Outcomes focus on functional vitality and cardiopulmonary fitness, using standard assessments appropriate for this population. The lead sponsor is Cairo University, with the trial conducted at Cairo University in Dokki, Giza.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* childhood-onset lupus
* adolescents who survived from intensive care unit
* adlescents who are in risk of developing pos-tintenive care-unit syndrome (i.e patients who admitted to an intenive care unit for at least four days in last year)

Exclusion Criteria:

* mental diseases
* upper or lower limb fractures

Where it's running

• Cairo University
  Dokki, Giza Governorate, Egypt Recruiting

Study contacts

• Principal investigator: Ali MA Ismail, lecturer — Department of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics
• Study coordinator: Ali MA Ismail, PhD
• Email: ali.mohamed@pt.cu.edu.eg
• Phone: +201005154209

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Budoprutug in systemic lupus erythematosus (SLE)

  A phase 1b/2a study in adults with active SLE will test two-dose levels of Budoprutug given by two IV infusions 14 days apart to see if it lowers B cells and improves disease activity in people who haven’t fully responded to standard therapy.

  Recruiting at 3 sites Phase 1/2 Climb Bio, Inc. · Mianyang, Sichuan and 9 other locations · NCT07564596

• Virtual reality cognitive training for ICU delirium survivors

  This project will try virtual reality brain games at home to see if they help memory, attention, and mood in older adults who had delirium after a critical illness.

  Recruiting Indiana University · Indianapolis, Indiana · NCT07496255

• GR1803 for systemic lupus erythematosus (SLE)

  This trial will test GR1803 injections in people with active systemic lupus (SLE) to see if the drug is safe and helps control lupus symptoms.

  Recruiting Phase 1/2 Genrix (Shanghai) Biopharmaceutical Co., Ltd. · Wuhan, Hubei · NCT07348055

• Post-ICU persistent pain in survivors

  This study will try to find how common and what causes long-lasting pain in adults who spent at least 48 hours in an ICU in Denmark.

  Recruiting at 3 sites Zealand University Hospital · Aalborg and 3 other locations · NCT07180407

• BCD-256 alone or with divozilimab for lupus skin lesions

  This will test whether BCD-256 by itself or together with divozilimab helps adults with mild-to-moderate systemic lupus who have active skin lesions.

  Recruiting Phase 1 Biocad · Saint Petersburg · NCT07136389

• Descartes-08 treatment for children, teens, and young adults with select autoimmune diseases

  This trial will test whether Descartes-08 is safe and can help control disease in children, adolescents, and young adults with childhood-onset lupus, ANCA-associated vasculitis, juvenile myasthenia gravis, or juvenile dermatomyositis.

  Recruiting at 3 sites Phase 1/2 Cartesian Therapeutics · Washington D.C., District of Columbia and 2 other locations · NCT07089121

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.