Guiding strategies to prevent and treat low blood pressure during surgery
Effectiveness of Peripheral Perfusion Index Guided Strategies for the Prevention and Treatment of Hypotension: a Randomized Trial
This study is testing ways to keep blood pressure stable during surgery to help patients avoid complications related to low blood pressure.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 54 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Tongji Hospital Academic / other |
| Locations | 1 site (Wuhan) |
| Trial ID | NCT05792696 on ClinicalTrials.gov |
What this trial studies
This study focuses on the prevention and treatment of intraoperative hypotension, a condition that can lead to serious complications during and after surgery. It aims to establish effective strategies based on maintaining a normal peripheral perfusion index (PPI) to manage blood pressure during anesthesia. The study will monitor patients undergoing general anesthesia for non-cardiac surgeries lasting more than two hours, ensuring that their mean arterial pressure remains above 65 mmHg. By implementing these strategies, the study seeks to reduce the risks associated with low blood pressure during surgical procedures.
Who should consider this trial
Good fit: Ideal candidates for this study are patients aged 65 years and older who are undergoing general anesthesia for procedures lasting more than two hours and can communicate in Mandarin.
Not a fit: Patients with a history of diabetes, vascular diseases, or those with cardiac function class II and above may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly reduce the incidence of complications related to intraoperative hypotension, improving surgical outcomes for patients.
How similar studies have performed: Other studies have shown promising results with similar approaches to managing intraoperative hypotension, indicating that this methodology is both relevant and potentially effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 65 years and older ASA Physical Status 1-3 general anesthesia arterial catheterization procedures last more than 2 hours communicate normally in Mandarin Exclusion Criteria: abnormal Allen's test higher target than 65 mmHg history of diabetes vascular diseases arrhythmia cardiac function class II and above physical disability, unable to conduct PPI monitoring participated in other clinical studies in the past month
Where this trial is running
Wuhan
- Zhiqiang Zhou — Wuhan, China (Recruiting)
Study contacts
- Principal investigator: Zhiqiang Zhou — Tongji Hospital
- Study coordinator: Zhiqiang Zhou, Dr.
- Email: zqzhou@tjh.tjmu.edu.cn
- Phone: 862783663173
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.