Guided cycling, non-contact boxing, and physical therapy for movement, fitness, and quality of life in Parkinson's disease
Changes in Motor Function, Quality of Life, Cardiorespiratory Fitness, and Physiological Markers in People With Parkinson's Disease Following Different Exercise Interventions.
This study will test whether guided cycling, non-contact boxing, or standard physical therapy best improve movement, fitness, and quality of life for adults with Parkinson's disease.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 45 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | University of Texas, El Paso Academic / other |
| Locations | 2 sites (El Paso, Texas and 1 other locations) |
| Trial ID | NCT07221266 on ClinicalTrials.gov |
What this trial studies
This randomized, controlled, parallel-group trial assigns adults with idiopathic Parkinson's disease to guided cycling, non-contact boxing, or traditional physical therapy delivered twice weekly for eight weeks. Interventions are supervised by licensed physical therapists in outpatient and community settings with intensity tailored to each participant. Outcomes include motor function, cardiorespiratory fitness, and physiological health markers measured at baseline, after the intervention, and following a four-week washout. Total participation is about 15 weeks to capture immediate training effects and short-term retention.
Who should consider this trial
Good fit: Ideal candidates are ambulatory adults aged 50 or older with idiopathic Parkinson's disease at Hoehn and Yahr stage 1–3 who are medically stable and speak English or Spanish.
Not a fit: People with advanced disease (Hoehn and Yahr stage 4–5), non-ambulatory individuals, or those with recent stroke, recent heart attack, unmanaged Parkinson's medications, or significant osteoporosis are unlikely to benefit or may be excluded.
Why it matters
Potential benefit: If successful, the results could identify which exercise approach most effectively improves movement, endurance, and daily function for people with Parkinson's disease.
How similar studies have performed: Previous trials show exercise benefits people with Parkinson's and separate studies report benefits from high-intensity cycling and boxing, but direct head-to-head comparisons of these specific approaches are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Diagnosis of Parkinson's Disease 2. Independent ambulation 3. Hoehn and Yahr stage of 1-3 4. 50 years of age or older 5. Must speak English or Spanish Exclusion Criteria: 1. History of stroke 2. History of heart attack 3. Non-ambulatory 4. Hoehn and Yahr of stage 4 or 5 5. Osteoporosis 6. Unmanaged Parkinson's medication
Where this trial is running
El Paso, Texas and 1 other locations
- University of Texas at El Paso Doctor of Physical Therapy and Movement Sciences Building — El Paso, Texas, United States (Recruiting)
- Move Therapy Services — El Paso, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Katherine M Reyes-Brooks, PT, DPT — University of Texas, El Paso
- Study coordinator: Katherine M Reyes-Brooks, PT, DPT
- Email: kmreyesbrooks@utep.edu
- Phone: 915-747-6122
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.