GPS tracking to support Hepatitis C treatment for people experiencing unsheltered homelessness.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized interventional project enrolls people with confirmed Hepatitis C who are experiencing unsheltered homelessness and receiving street medicine in Southern California. Participants are randomly assigned to receive standard Hepatitis C care delivered by street medicine teams with or without a GPS tracker device to assist outreach and follow-up. The primary outcome is medication adherence and treatment completion over the typical 8–12 week therapy course, with mixed-methods data collection to understand barriers and acceptability. The protocol emphasizes ethical, privacy-conscious use of location technology and practical approaches to longitudinal follow-up in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosed with Hepatitis C infection
* Experiencing unsheltered homelessness at study initiation
* Speaks English or Spanish
* Receiving street medicine care
* Meet the American Association for the Study of Liver Diseases (AASLD) criteria for simplified treatment of Hepatitis C

Exclusion Criteria:

* Prior engagement in HCV treatment
* Decompensated cirrhosis; HBsAg positive
* Current pregnancy; Known or suspended hepatocellular carcinoma
* Prior liver transplantation

Where it's running

• USC Street Medicine
  Alhambra, California, United States Recruiting
• Ventura County Medical Center
  Ventura, California, United States Recruiting

Study contacts

• Principal investigator: Camilo Zaks, MD — University of Southern California, Keck School of Medicine of USC, Department of Family Medicine, USC Street Medicine
• Study coordinator: Alexis Coulourides Kogan, PhD
• Email: acoulour@usc.edu
• Phone: 626-457-4207

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.