Glutamine supplementation for gastric cancer patients after surgery
Oral Supplementation of Glutamine on Gastric Cancer Patients After Gastrectomy
NA · National Taiwan University Hospital · NCT06027242
This study is testing if taking glutamine can help gastric cancer patients recover better after surgery by improving their muscle strength and overall health.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | National Taiwan University Hospital (other) |
| Locations | 1 site (Taipei) |
| Trial ID | NCT06027242 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effects of oral glutamine on patients with gastric adenocarcinoma who are undergoing gastrectomy. It is a double-blind, randomized, placebo-controlled trial involving at least 80 patients, who will be divided into treatment and control groups. The primary focus is on the efficacy of glutamine in addressing sarcopenia, while secondary endpoints include assessments of physical activity, weight loss, and nutritional profiles. Patients will undergo CT scans and wear smartwatches to monitor their daily activity levels before and after surgery.
Who should consider this trial
Good fit: Ideal candidates are adult patients diagnosed with gastric cancer who are scheduled for gastrectomy.
Not a fit: Patients with hepatic or renal insufficiency, or those unable to tolerate oral feeding or wear monitoring devices, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve recovery and nutritional status in gastric cancer patients post-surgery.
How similar studies have performed: Other studies have shown promising results with glutamine supplementation in similar patient populations, suggesting potential efficacy.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * adult gastric cancer receiving gastrectomy Exclusion Criteria: * Hepatic insufficiency * Renal insufficiency * can not tolerate oral or enteral feeding 7 days after gastrectomy * can not receive computed tomograph * can not waer the wearable devices
Where this trial is running
Taipei
- National Taiwan University Hospital — Taipei, Taiwan (RECRUITING)
Study contacts
- Principal investigator: Jin-Ming Wu, MD — National Taiwan University Hospital
- Study coordinator: Jin-Ming Wu, MD
- Email: wujm0531@gmail.com
- Phone: 886+223123456
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gastric Cancer, Immunonutrition, Gastrostomy, Gastric cancer, Gastrectomy, sarcopenia