Glutamine supplementation for gastric cancer patients after surgery
Official title: Oral Supplementation of Glutamine on Gastric Cancer Patients After Gastrectomy
Run by National Taiwan University Hospital · NCT06027242 · Data updated 2026-11-12
This study is testing if taking glutamine can help gastric cancer patients recover better after surgery by improving their muscle strength and overall health.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years and up |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | February 21, 2023 |
| Main results expected | August 30, 2026 |
| Study ends | August 30, 2026 |
| Registry record updated | December 23, 2025 |
| Trial ID | NCT06027242 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adult patients diagnosed with gastric cancer who are scheduled for gastrectomy.
✕Probably not a fit
Patients with hepatic or renal insufficiency, or those unable to tolerate oral feeding or wear monitoring devices, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effects of oral glutamine on patients with gastric adenocarcinoma who are undergoing gastrectomy. It is a double-blind, randomized, placebo-controlled trial involving at least 80 patients, who will be divided into treatment and control groups. The primary focus is on the efficacy of glutamine in addressing sarcopenia, while secondary endpoints include assessments of physical activity, weight loss, and nutritional profiles. Patients will undergo CT scans and wear smartwatches to monitor their daily activity levels before and after surgery.
Why it matters
Potential benefit: If successful, this study could improve recovery and nutritional status in gastric cancer patients post-surgery.
How similar studies have gone: Other studies have shown promising results with glutamine supplementation in similar patient populations, suggesting potential efficacy.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * adult gastric cancer receiving gastrectomy Exclusion Criteria: * Hepatic insufficiency * Renal insufficiency * can not tolerate oral or enteral feeding 7 days after gastrectomy * can not receive computed tomograph * can not waer the wearable devices
Where it's running
-
National Taiwan University Hospital
Taipei, Taiwan Recruiting
Study contacts
- Principal investigator: Jin-Ming Wu, MD — National Taiwan University Hospital
- Study coordinator: Jin-Ming Wu, MD
- Email: wujm0531@gmail.com
- Phone: 886+223123456
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Comparing stapler reinforcement patches to standard staplers in gastrojejunostomy procedures
This study tests if using special patches with staplers during gastric cancer surgery can help prevent complications like leaks compared to regular staplers.
-
CG-7321: a first-in-human test in advanced solid tumors
We’re testing CG-7321 alone and with fulvestrant to see if it’s safe and tolerable in adults with advanced solid tumors.
-
Neoadjuvant trastuzumab, durvalumab, and FLOT for HER2-positive gastric or GEJ cancer
This study tests a pre-surgery treatment combining trastuzumab, durvalumab, and FLOT for patients with HER2-positive locally advanced gastric or gastroesophageal junction cancer to see how many achieve complete tumor disappearance.
-
Integrated genomic and clinical database for cancer biomarker discovery
Researchers are building a combined genomic and clinical database at Samsung Medical Center to test biomarkers for cancer diagnosis, treatment choice, and predicting how well treatments work.
-
Adding 2141-V11 to standard therapy for advanced esophageal, gastric, or gastroesophageal junction cancer
This study tests whether adding the drug 2141-V11 to standard anti-PD-1 therapy (with or without 5-FU) is safe for adults with advanced or metastatic esophageal, gastric, or gastroesophageal junction adenocarcinoma.
-
Guaraná Supplement for Cancer-Related Fatigue in People Undergoing Treatment
This study tests whether taking guaraná capsules helps reduce cancer-related fatigue and improve quality of life in adults with breast, lung, colorectal, or gastric cancer who are actively receiving treatment.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.