Global registry of transcatheter tricuspid valve replacement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The TRIPLACE Registry is a global, multicenter observational program collecting clinical and procedural data on adults undergoing orthotopic transcatheter tricuspid valve replacement (TTVR). Participating centers will record procedural details, in-hospital events, conduction disturbances including timing of permanent pacemaker implantation, and long-term clinical outcomes. Analyses will explore how pre- and post-procedural factors relate to peri-procedural complications and subsequent adverse events. Enrollment is limited to patients treated as part of routine care at participating sites.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients undergoing Transcatheter Tricuspid Valve Replacement
* Native Tricuspid Valve disease
* Orthotopic Tricuspid Valve Implantation

Exclusion Criteria:

* Age under 18 years

Where it's running

• Arizona Heart Hospital (Biltmore Cardiology)
  Phoenix, Arizona, United States Recruiting
• Ascension Via Christi
  Wichita, Kansas, United States Recruiting
• Hackensack University Medical Center
  Hackensack, New Jersey, United States Recruiting
• Columbia University Irving Medical Center
  New York, New York, United States Recruiting
• Montefiore Medical Center
  The Bronx, New York, United States Recruiting
• The Christ Hospital
  Cincinnati, Ohio, United States Recruiting

Study contacts

• Principal investigator: Andrea Scotti, MD — Montefiore Medical Center
• Study coordinator: Andrea Scotti, MD
• Email: ascotti@montefiore.org
• Phone: 7189043388

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• 3D Echocardiography to See How CIEDs May Worsen Tricuspid Regurgitation

  This study tests whether different CIEDs (leadless pacemakers, LBBaP, and conventional pacemakers) differ in causing worsening tricuspid regurgitation, using 3D heart imaging.

  Recruiting Samsung Medical Center · Seoul, Seoul · NCT07793916

• Compare leadless and left bundle branch pacemakers for heart and valve function

  This study tests whether leadless pacemakers or left bundle branch area pacing better preserve heart and tricuspid valve function in adults needing a pacemaker.

  Recruiting Guy's and St Thomas' NHS Foundation Trust · London · NCT07534917

• TriClip for treating tricuspid regurgitation in Japan

  This study will see if the TriClip device is safe and helps people in Japan with symptomatic severe tricuspid regurgitation when used in routine clinical care.

  Recruiting Abbott Medical Devices · Suita, Osaka · NCT07509658

• Impact of transcatheter tricuspid valve repair on kidneys, strength, and activity in older adults

  This study will try catheter-based tricuspid valve repair (TEER) in older adults with severe symptomatic tricuspid regurgitation to see if kidney function, fluid overload, and physical activity improve.

  Recruiting Robert Bosch Medical Center · Stuttgart · NCT07464106

• TARGET 2.0: Cardiovalve TR replacement for tricuspid regurgitation

  This study will test a percutaneously delivered Cardiovalve tricuspid replacement via the femoral vein in adults with symptomatic severe secondary tricuspid regurgitation who are high risk for open-heart surgery.

  Recruiting Cardiovalve Ltd. · Bonn · NCT07334691

• Pivot Extend device to treat severe tricuspid regurgitation

  This trial will try the Pivot Extend device in adults with severe, symptomatic tricuspid regurgitation to see if it safely reduces valve leakage and improves symptoms.

  Recruiting Tau-MEDICAL Co., Ltd. · Macquarie Park, New South Wales · NCT07172477

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.