Clinical trial Recruiting at 1 site Observational Ages 18 and up

Global look at how cancer affects appearance

Official title: The GRACE Study - Global Research on Appearance in Cancer

Run by Karolinska Institutet · NCT07195448 · Data updated 2026-11-12

This project will see how adults with advanced cancer from eight countries notice and feel about weight loss.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment800 (estimated)
SponsorKarolinska Institutet
Academic / other
Locations1 site (Stockholm)
StatusRecruiting
StartedFebruary 10, 2025
Main results expectedApril 2026
Study endsDecember 2026
Registry record updatedOctober 1, 2025
Trial IDNCT07195448 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) with a clinical diagnosis of advanced cancer, an expected survival of more than three months, and the ability to understand the consent form are ideal candidates.

Probably not a fit

Patients with an expected survival under three months or those unable to complete an anonymous digital questionnaire are unlikely to gain direct benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multi-country cross-sectional survey will invite 50 men and 50 women (100 total) aged 18 and older with advanced cancer from eight countries to complete an anonymous, one-time digital questionnaire accessed by a QR code at participating cancer clinics. Collected data include current weight and weight history, height, previous weight-loss attempts, education, marital status, body image measured by the Body Image Scale, nutrition-impact symptoms using the Edmonton Symptom Assessment Scale, and recent dietary choices. No personal identifiers are collected, and Body Image Scale missing items will be handled per the scoring protocol while other missing data will be analyzed as complete cases without imputation. The investigators intend to compare perceptions of weight loss across genders and countries to inform gender-sensitive nutrition recommendations in palliative care.

Why it matters

Potential benefit: If successful, results could help shape gender-sensitive medical nutrition guidance to improve quality of life and potentially disease outcomes for people with advanced cancer.

How similar studies have gone: Previous observational surveys have explored body image and weight loss in cancer patients, but this eight-country, gender-balanced approach is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical diagnosis of cancer
* Must be able to understand the consent form

Exclusion Criteria:

\- Expected survival time \< 3 months

Where it's running

  • Karolinska Institutet
    Stockholm, Sweden
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.