Global assessment of keratoconus prevalence in children and adolescents

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the prevalence of keratoconus in children and adolescents across various global regions using advanced tomographic imaging techniques. By conducting bilateral corneal tomography examinations on participants aged 6 to 20 years who are visiting for non-ophthalmologic reasons, the study seeks to determine if the actual prevalence of keratoconus is higher than previously reported. The research will take place in multiple cities across North America, South America, Asia, and Europe, providing a comprehensive view of the condition's prevalence worldwide.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male or female, 6-23 years of age.
* Subjects seen for a non-ophthalmic appointment
* Provide signed and dated patient consent form (signed by parents / legal guardians).
* Willing to comply with all study procedures and be available for the duration of the study

Exclusion Criteria:

* Patients with a preexisting ocular disease / condition
* Pregnancy or breastfeeding

Where it's running

• USC Roski Eye Institute
  Los Angeles, California, United States Recruiting
• Eye Hospital of Wenzhou Medical College
  Wenzhou, China Recruiting
• Zagreb, Croatia Recruiting
• Alexandria, Egypt Recruiting
• Homburg, Germany Recruiting
• Isfahan, Iran Recruiting

Study contacts

• Study coordinator: Farhad Hafezi, MDPhD
• Email: fhafezi@elza-institute.com
• Phone: +41 44 741 81 81

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Corneal Crosslinking to Treat Progressive Keratoconus or Corneal Ectasia

  This study tests two different light durations used in corneal crosslinking to see which better helps people with keratoconus or corneal ectasia.

  Recruiting Phase 2/3 Price Vision Group · Indianapolis, Indiana · NCT07841470

• Brillouin hydration mapping to study cornea health

  Researchers test a Brillouin microscope to see if it can measure corneal water content in healthy people and those with eye conditions.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT07780890

• Same-day bilateral corneal cross-linking for keratoconus

  This trial tests whether performing corneal cross-linking in both eyes on the same day is safe and feasible for people with keratoconus.

  Recruiting Phase 4 Glaukos Corporation · Westerville, Ohio · NCT07629557

• A Smart Aperture Lens to Help Keratoconus and Presbyopia

  This study tests the NOA lens, a custom scleral contact lens with a central aperture, to see if it improves vision for people with keratoconus and presbyopia.

  Recruiting at 2 sites Azalea Vision · Antwerp and 1 other locations · NCT07559188

• GLK-221 eye drops for keratoconus

  This trial will test whether twice-daily GLK-221 eye drops are safe and help adults aged 18–55 with keratoconus compared with a placebo.

  Recruiting Phase 2 Glaukos Corporation · Westerville, Ohio · NCT07400952

• Corneal wavefront-guided PRK plus epi-off CXL versus PTK plus epi-off CXL for keratoconus

  This trial tests whether adding corneal wavefront-guided PRK to epi-off corneal cross-linking gives better vision than PTK plus epi-off CXL in adults with keratoconus.

  Recruiting Instituto de Oftalmología Fundación Conde de Valenciana · Mexico City, Mexico City · NCT07372911

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.