Global assessment of keratoconus prevalence in children and adolescents
The K-Map Study, Global Prevalence of KC
This study is trying to find out how common keratoconus is in kids and teens around the world by using special eye imaging techniques.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 20000 (estimated) |
| Ages | 6 Years to 23 Years |
| Sex | All |
| Sponsor | University Hospital, Geneva Academic / other |
| Locations | 12 sites (Los Angeles, California and 11 other locations) |
| Trial ID | NCT03115710 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the prevalence of keratoconus in children and adolescents across various global regions using advanced tomographic imaging techniques. By conducting bilateral corneal tomography examinations on participants aged 6 to 20 years who are visiting for non-ophthalmologic reasons, the study seeks to determine if the actual prevalence of keratoconus is higher than previously reported. The research will take place in multiple cities across North America, South America, Asia, and Europe, providing a comprehensive view of the condition's prevalence worldwide.
Who should consider this trial
Good fit: Ideal candidates for this study are children and adolescents aged 6 to 20 years who are attending medical appointments for non-ophthalmologic reasons.
Not a fit: Patients with preexisting ocular diseases or conditions, as well as those who are pregnant or breastfeeding, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and awareness of keratoconus prevalence, potentially influencing early detection and treatment strategies.
How similar studies have performed: While there have been studies on keratoconus, this approach of assessing global prevalence using modern imaging techniques is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female, 6-23 years of age. * Subjects seen for a non-ophthalmic appointment * Provide signed and dated patient consent form (signed by parents / legal guardians). * Willing to comply with all study procedures and be available for the duration of the study Exclusion Criteria: * Patients with a preexisting ocular disease / condition * Pregnancy or breastfeeding
Where this trial is running
Los Angeles, California and 11 other locations
- USC Roski Eye Institute — Los Angeles, California, United States (Recruiting)
- Eye Hospital of Wenzhou Medical College — Wenzhou, China (Recruiting)
- Zagreb, Croatia (Recruiting)
- Alexandria, Egypt (Recruiting)
- Homburg, Germany (Recruiting)
- Isfahan, Iran (Recruiting)
- Amman, Jordan (Recruiting)
- Monterrey, Mexico (Recruiting)
- Lima, Peru (Recruiting)
- Ufa Eye Research Intitute — Ufa, Russia (Completed)
- King Saud University — Riyadh, Saudi Arabia (Completed)
- Bukhara, Uzbekistan (Recruiting)
Study contacts
- Study coordinator: Farhad Hafezi, MDPhD
- Email: fhafezi@elza-institute.com
- Phone: +41 44 741 81 81
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.