Giving ketorolac for pain after egg retrieval in fresh embryo transfer IVF cycles

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a double-blind, randomized controlled trial comparing a single 30 mg IV dose of ketorolac given at the end of oocyte retrieval versus usual care without ketorolac. Participants are randomized 1:1 with block randomization while still under sedation, and all undergo standard IVF and a planned day-5 fresh embryo transfer. Study staff will collect clinical data and follow outcomes including post-operative pain, bleeding, and IVF success measures through medical record review for up to 45 weeks. The trial focuses on autologous IVF cycles and permits standard stimulation and insemination methods used at the center.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* IVF utilizing autologous oocytes and all sperm sources
* IVF cycles utilizing ICSI and standard insemination
* Plan to transfer embryo on day 5
* BMI below 50

Exclusion Criteria:

-allergies or medical contraindications to NSAIDs

Where it's running

• UI Health Care Center for Advanced Reproductive Care
  Iowa City, Iowa, United States Recruiting

Study contacts

• Study coordinator: Jessica Kresowik, MD
• Email: jessica-kresowik@uiowa.edu
• Phone: 563-355-2244

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.