Giving IV clot-busting medicine for ischemic stroke 4.5–24 hours after last known normal

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multicenter, retrospective, observational cohort study collecting past clinical records of adults with acute ischemic stroke who received intravenous thrombolysis 4.5–24 hours after last known well. Investigators will extract demographic and clinical data including age, sex, NIHSS, and mRS, and will compare clinical outcomes and safety signals among patients treated with agents such as alteplase or tenecteplase. Because it is retrospective, treatment decisions were made clinically and the study will analyze real-world effectiveness and complications rather than assigning treatments prospectively. Results will aim to identify which patients, if any, might benefit from later thrombolytic therapy and what risks are associated.

Why it matters

Who can join: the full rules

1. Patients with acute ischemic stroke, regardless of gender;
2. Age ≥ 18 years old;
3. Time from onset to treatment within 4.5 - 24 hours (the onset time refers to the last time when they appeared normal);
4. Complete relevant clinical data (including gender, age, mRS, NIHSS, etc.).

Where it's running

• Xuanwu Hospital Capital Medical University, Beijing, Beijing 100053
  Beijing, China Recruiting

Study contacts

• Study coordinator: Xin Xing, MD
• Email: drxingxin@126.com
• Phone: 01083198082

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Deep phenotyping to explore recovery in young adults after stroke

  This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.

  Recruiting The Florey Institute of Neuroscience and Mental Health · Heidelberg, Victoria and 1 other locations · NCT07019493

• Stem cell therapy for chronic stroke recovery

  This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.

  Recruiting Phase 2 Hokkaido University Hospital · Sapporo, Hokkaido · NCT06752720

• AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals

  This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.

  Recruiting at 2 sites Hospital Universitari Vall d'Hebron Research Institute · Leuven and 6 other locations · NCT07924371

• Web-based therapy using action observation and mirror therapy for arm weakness after stroke

  This trial tests whether a mobile telerehabilitation app delivering action observation therapy (AOT) alone or combined AOT with mirror therapy (AOT-MT) can improve upper limb function in people with subacute stroke.

  Recruiting Chang Gung Memorial Hospital · Taoyuan · NCT07921108

• Remote Ischaemic Conditioning for Fatigue After Stroke 2

  Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.

  Recruiting Phase 2 Sheffield Teaching Hospitals NHS Foundation Trust · Sheffield, South Yorkshire · NCT07914647

• Dual-task balance training plus computer-based cognitive training after stroke

  In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.

  Recruiting Matia Foundation · San Sebastián, GUIPUZCOA · NCT07913620

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.