Genicular nerve block for improving knee function in osteoarthritis
Investigation of the Effect of Ultrasound-Guided Genicular Nerve Block on Knee Joint Proprioception in Patients with Chronic Knee Osteoarthritis
NA · Ankara City Hospital Bilkent · NCT06744842
This study tests if a special injection near the knee nerves can help people with osteoarthritis feel less pain and improve their knee function.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 44 (estimated) |
| Ages | 55 Years to 75 Years |
| Sex | All |
| Sponsor | Ankara City Hospital Bilkent (other) |
| Locations | 1 site (Ankara, Çankaya) |
| Trial ID | NCT06744842 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of genicular nerve block on pain relief, quality of life, and proprioception in individuals suffering from knee osteoarthritis. The procedure involves administering local anesthetics and corticosteroids near specific genicular nerves using ultrasound guidance, aiming to provide temporary pain relief. The study also assesses proprioception, which is often impaired in osteoarthritis, to better understand how the treatment may influence joint awareness and function. Participants will be evaluated based on their knee pain and functional status before and after the intervention.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 55 to 75 with a diagnosis of bilateral primary knee osteoarthritis classified as Grade 2 or 3.
Not a fit: Patients with recent knee trauma, prior knee surgery, or those with certain health conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce pain and improve the quality of life for patients with knee osteoarthritis.
How similar studies have performed: Previous studies have shown promising results with genicular nerve blocks for pain management in knee osteoarthritis, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of bilateral primary knee osteoarthritis according to ACR (American College of Rheumatology) criteria. * Age between 55 and 75 years. * Presence of knee osteoarthritis classified as Grade 2 or Grade 3 according to the Kellgren-Lawrence grading system on radiographs taken within the last year. * Knee pain lasting longer than 6 months. * Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, total score 48-96 Exclusion Criteria: * Severe knee trauma within the last 6 months. * History of surgical operation on the knee region. * Intra-articular steroid and/or hyaluronate injection into the knee joint within the last 6 months. * Physical therapy targeting the knee within the last 6 months. * Regular use of NSAIDs within the last 6 months. * Presence of acute synovitis. * Neurological deficits in the lower extremity. * Presence of an inflammatory disease. * Poor general health condition (e.g., heart failure, advanced asthma, history of malignancy). * Any endocrine disorder that may cause polyneuropathy.
Where this trial is running
Ankara, Çankaya
- Ankara Bilkent City Hospital — Ankara, Çankaya, Turkey (RECRUITING)
Study contacts
- Study coordinator: Beyza Afşin Bener, Medical Doctor
- Email: beafsin@gmail.com
- Phone: +905418896209
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Osteoarthritis, Genicular nerve block, Proprioception