Genicular artery embolization for knee osteoarthritis — patient registry
Official title: Creation Of a Prospective Registry For Genicular Artery Embolization At The Joint & Vascular Institute
Run by Joint & Vascular Institute · NCT07380906 · Data updated 2026-11-12
This registry will try genicular artery embolization (GAE) in adults with knee osteoarthritis whose pain hasn't improved with medicines to see if it reduces pain and improves quality of life over months to years.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1200 (estimated) |
| Sponsor | Joint & Vascular Institute Industry-sponsored |
| Locations | 1 site (Libertyville, Illinois) |
| Status | Recruiting |
| Started | July 16, 2025 |
| Main results expected | April 2030 |
| Study ends | July 2030 |
| Registry record updated | June 12, 2026 |
| Trial ID | NCT07380906 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older with symptomatic knee osteoarthritis that has not improved with medical therapy and who are referred for GAE are ideal candidates for enrollment.
✕Probably not a fit
People who are pregnant, have significant bleeding disorders, severe uncontrolled comorbidities, or cannot consent are unlikely to be eligible or to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective registry will collect real-world safety and effectiveness data on genicular artery embolization (GAE) performed as part of routine care for adults with symptomatic knee osteoarthritis refractory to medical therapy. Participants will complete standardized symptom and quality-of-life questionnaires, including pain scores (WOMAC, VAS), at 1, 3, 6, 12, 18, 24, and 36 months after the procedure. Safety events will be tracked using Society of Interventional Radiology guidelines. There is no control group; data will be analyzed to identify patient and procedural factors associated with better outcomes and to inform best practices.
Why it matters
Potential benefit: If successful, the registry could show that GAE provides sustained pain relief and improved function for some people with knee osteoarthritis who have not responded to medical treatment.
How similar studies have gone: Early and small observational studies and case series have reported symptomatic improvement after GAE, but long-term, larger-scale real-world data remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (≥18 years) with symptomatic KOA refractory to medical therapy, referred for GAE. Exclusion Criteria: * Pregnancy, coagulopathy, severe comorbidities, or inability to consent.
Where it's running
-
Joint and Vascular Institute
Libertyville, Illinois, United States Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.