Genetic testing for cancer risk in women visiting gynecology clinics

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research aims to evaluate the feasibility and acceptability of offering genetic testing for cancer-related genes to female patients aged 25-39 during their gynecology clinic visits. The study will assess how many patients choose to undergo genetic testing and the proportion of those who have pathogenic variants. By integrating genetic testing into routine gynecological care, the study seeks to simplify access to important cancer risk information without requiring specialized referrals. The intervention involves the Natera® Empower™ hereditary cancer panel test.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Female patients between ages of 25-39 years at the time of visit
2. Receive gynecologic care at an affiliated NYU Langone Health (NYULH) site listed in this protocol.

Exclusion Criteria:

1. Personal history of ovarian, fallopian tube, primary peritoneal, or uterine cancers
2. Previously undergone germline testing for ovarian cancer risk variants (prior commercial saliva-based kits, such as 23andMe, are acceptable)
3. History of bilateral salpingo-oophorectomy
4. Visit related to pregnancy or immediately postpartum (within 2 weeks)

Where it's running

• NYU Langone Health
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Bhavana Pothuri, MD, MS — NYU Langone Health
• Study coordinator: Bhavana Pothuri, MD, MS
• Email: Bhanava.pothuri@nyulangone.org
• Phone: 212-731-6455

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.